Effects of persistent sodium current blockade in respiratory circuits depend on the pharmacological mechanism of action and network dynamics

Ryan S. Phillips; Jonathan E. Rubin

doi:10.1371/journal.pcbi.1006938

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Open Access

Peer-reviewed

Research Article

Effects of persistent sodium current blockade in respiratory circuits depend on the pharmacological mechanism of action and network dynamics

Ryan S. Phillips ,

Roles Conceptualization, Formal analysis, Investigation, Software, Writing – original draft, Writing – review & editing

* E-mail: RyanP@pitt.edu

Affiliation Department of Mathematics and Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

http://orcid.org/0000-0002-8570-2348

⨯
Jonathan E. Rubin

Roles Conceptualization, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Mathematics and Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

http://orcid.org/0000-0002-1513-1551

⨯

Effects of persistent sodium current blockade in respiratory circuits depend on the pharmacological mechanism of action and network dynamics

Ryan S. Phillips,
Jonathan E. Rubin

Published: August 30, 2019
https://doi.org/10.1371/journal.pcbi.1006938

About the Authors

Ryan S. Phillips

Roles Conceptualization, Formal analysis, Investigation, Software, Writing – original draft, Writing – review & editing

* E-mail: RyanP@pitt.edu

Affiliation Department of Mathematics and Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

http://orcid.org/0000-0002-8570-2348

Jonathan E. Rubin

Roles Conceptualization, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Mathematics and Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

http://orcid.org/0000-0002-1513-1551

Competing Interests

The authors have declared that no competing interests exist.

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Pacemakers
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Hyperpolarization
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