About the Authors

He Peng

Roles Investigation, Methodology, Software, Visualization, Writing – original draft

Affiliation Department of Computer Science, Xiamen University, Xiamen, Fujian, China

Xiangxiang Zeng

Roles Investigation, Methodology, Supervision, Visualization

xzeng@xmu.edu.cn (XZ); nussinor@mail.nih.gov (RN); chengf@ccf.org (FC)

Affiliation Department of Computer Science, Xiamen University, Xiamen, Fujian, China

Yadi Zhou

Roles Formal analysis, Investigation, Visualization

Affiliation Department of Chemistry and Biochemistry, Ohio University, Athens, OH, United States of America

Defu Zhang

Roles Formal analysis

Affiliation Department of Computer Science, Xiamen University, Xiamen, Fujian, China

Ruth Nussinov

Roles Validation, Writing – review & editing

xzeng@xmu.edu.cn (XZ); nussinor@mail.nih.gov (RN); chengf@ccf.org (FC)

Affiliations Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, United States of America, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

Feixiong Cheng

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

xzeng@xmu.edu.cn (XZ); nussinor@mail.nih.gov (RN); chengf@ccf.org (FC)

Affiliations Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States of America, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, United States of America, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America

Competing Interests

The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products or organizations imply endorsement by the US Government. The authors have declared that no competing interests exist.