About the Authors

Yiming Hu

Contributed equally to this work with: Yiming Hu, Qiongshi Lu

Affiliation Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States of America

Qiongshi Lu

Contributed equally to this work with: Yiming Hu, Qiongshi Lu

Affiliation Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States of America

Ryan Powles

Affiliation Program of Computational Biology and Bioinformatics, Yale University, New Haven, CT, United States of America

Xinwei Yao

Affiliation Yale College, New Haven, CT, United States of America

Can Yang

Affiliation Department of Mathematics, Hong Kong Baptist University, Kowloon, Hong Kong

Fang Fang

Affiliation Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States of America

Xinran Xu

Affiliation Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States of America

Hongyu Zhao

hongyu.zhao@yale.edu

Affiliations Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States of America, Program of Computational Biology and Bioinformatics, Yale University, New Haven, CT, United States of America, Department of Genetics, Yale University School of Medicine, New Haven, CT, United States of America, Clinical Epidemiology Research Center (CERC), Veterans Affairs (VA) Cooperative Studies Program, VA Connecticut Healthcare System, West Haven, CT, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: YH QL HZ. Data curation: CY. Formal analysis: YH QL HZ. Methodology: YH QL HZ. Software: YH RP XY. Validation: YH QL FF XX CY. Writing – original draft: YH QL HZ.