Managing uncertainty in metabolic network structure and improving predictions using EnsembleFBA

Matthew B. Biggs; Jason A. Papin

doi:10.1371/journal.pcbi.1005413

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Open Access

Peer-reviewed

Research Article

Managing uncertainty in metabolic network structure and improving predictions using EnsembleFBA

Matthew B. Biggs,

Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, United States of America

http://orcid.org/0000-0001-6492-8180

⨯
Jason A. Papin

* E-mail: papin@virginia.edu

Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, United States of America
⨯

Managing uncertainty in metabolic network structure and improving predictions using EnsembleFBA

Matthew B. Biggs,
Jason A. Papin

Published: March 6, 2017
https://doi.org/10.1371/journal.pcbi.1005413
See the preprint

About the Authors

Matthew B. Biggs

Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, United States of America

http://orcid.org/0000-0001-6492-8180

Jason A. Papin

* E-mail: papin@virginia.edu

Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: MBB JP. Data curation: MBB. Formal analysis: MBB. Funding acquisition: JP. Investigation: MBB. Methodology: MBB JP. Project administration: JP. Resources: JP. Software: MBB. Supervision: JP. Validation: MBB. Visualization: MBB. Writing – original draft: MBB. Writing – review & editing: MBB JP.

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Small molecules
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Gene prediction
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Metabolic networks
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Pneumococcus
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