Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations

Andrew F. Neuwald; Stephen F. Altschul

doi:10.1371/journal.pcbi.1005294

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Open Access

Peer-reviewed

Research Article

Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations

Andrew F. Neuwald ,

* E-mail: aneuwald@som.umaryland.edu

Affiliation Institute for Genome Sciences and Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, BioPark II, Room 617, Baltimore, MD, United States of America
⨯
Stephen F. Altschul

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, United States of America

http://orcid.org/0000-0003-2120-9631

⨯

Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations

Andrew F. Neuwald,
Stephen F. Altschul

Published: December 21, 2016
https://doi.org/10.1371/journal.pcbi.1005294

About the Authors

Andrew F. Neuwald

* E-mail: aneuwald@som.umaryland.edu

Affiliation Institute for Genome Sciences and Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, BioPark II, Room 617, Baltimore, MD, United States of America

Stephen F. Altschul

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, United States of America

http://orcid.org/0000-0003-2120-9631

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: AFN. Formal analysis: AFN SFA. Investigation: AFN. Methodology: AFN SFA. Project administration: AFN. Software: AFN. Validation: AFN. Visualization: AFN. Writing – original draft: AFN. Writing – review & editing: AFN SFA.

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Sequence alignment
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Multiple alignment calculation
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Hidden Markov models
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Salt bridges
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Arginine
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Protein structure
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Probability distribution
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Protein structure comparison
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