About the Authors

Daifeng Wang

Affiliations Department of Biomedical Informatics, Stony Brook University, Stony Brook, New York, United States of America, Stony Brook Cancer Center, Stony Brook Medicine, Stony Brook, New York, United States of America

Fei He

Affiliation Biology Department, Brookhaven National Laboratory, Upton, New York, United States of America

Sergei Maslov

Affiliations Biology Department, Brookhaven National Laboratory, Upton, New York, United States of America, Department of Bioengineering and Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

Mark Gerstein

mark@gersteinlab.org

Affiliations Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, United States of America, Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America, Department of Computer Science, Yale University, New Haven, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DW MG. Performed the experiments: DW. Analyzed the data: DW FH. Contributed reagents/materials/analysis tools: DW FH SM. Wrote the paper: DW FH MG.