About the Authors

Julia Rex

Contributed equally to this work with: Julia Rex, Ute Albrecht

julia.rex@isys.uni-stuttgart.de

Affiliation Institute for System Dynamics, University of Stuttgart, Stuttgart, Germany

Ute Albrecht

Contributed equally to this work with: Julia Rex, Ute Albrecht

Affiliation Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich-Heine-University, Düsseldorf, Germany

Christian Ehlting

Affiliation Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich-Heine-University, Düsseldorf, Germany

Maria Thomas

Affiliation Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany

Ulrich M. Zanger

Affiliation Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany

Oliver Sawodny

Affiliation Institute for System Dynamics, University of Stuttgart, Stuttgart, Germany

Dieter Häussinger

Affiliation Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich-Heine-University, Düsseldorf, Germany

Michael Ederer

Affiliation Institute for System Dynamics, University of Stuttgart, Stuttgart, Germany

Ronny Feuer

‡RF and JGB also contributed equally to this work.

Affiliation Institute for System Dynamics, University of Stuttgart, Stuttgart, Germany

Johannes G. Bode

‡RF and JGB also contributed equally to this work.

Affiliation Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich-Heine-University, Düsseldorf, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: UA JGB JR RF ME MT. Performed the experiments: UA CE MT. Analyzed the data: JR UA RF. Wrote the paper: JR UA CE MT UMZ OS DH ME RF JGB. Mathematical Modelling: JR RF ME OS.