About the Authors

Amit A. Upadhyay

Affiliations Genome Science and Technology Graduate Program, University of Tennessee–Oak Ridge National Laboratory, Knoxville, Tennessee, United States of America, Department of Microbiology, University of Tennessee, Knoxville, Tennessee, United States of America, Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

Aaron D. Fleetwood

Affiliations Department of Microbiology, University of Tennessee, Knoxville, Tennessee, United States of America, Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

Ogun Adebali

Affiliations Genome Science and Technology Graduate Program, University of Tennessee–Oak Ridge National Laboratory, Knoxville, Tennessee, United States of America, Department of Microbiology, University of Tennessee, Knoxville, Tennessee, United States of America, Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

Robert D. Finn

Affiliation European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

Igor B. Zhulin

ijouline@utk.edu

Affiliations Genome Science and Technology Graduate Program, University of Tennessee–Oak Ridge National Laboratory, Knoxville, Tennessee, United States of America, Department of Microbiology, University of Tennessee, Knoxville, Tennessee, United States of America, Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IBZ AAU. Performed the experiments: AAU. Analyzed the data: AAU ADF OA RDF IBZ. Contributed reagents/materials/analysis tools: RDF. Wrote the paper: AAU ADF IBZ.