About the Authors

Takumi Higaki

Affiliation Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan

Natsumaro Kutsuna

Affiliations Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan, Research and Development Division, LPixel Inc., Tokyo, Japan

Kae Akita

Affiliation Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan

Hisako Takigawa-Imamura

Affiliation Department of Anatomy and Cell Biology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

Kenji Yoshimura

Affiliation Department of Neurology, Osaka City General Hospital, Osaka, Japan

Takashi Miura

miura_t@anat1.med.kyushu-u.ac.jp

Affiliation Department of Anatomy and Cell Biology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

Competing Interests

NK belongs to University of Tokyo but is also employed by LPixel Inc. He declares that he has no competing interest concerning employment, consultancy, patents, products in development or marketed products etc. described in http://journals.plos.org/ploscompbiol/s/competing-interests.

Author Contributions

Conceived and designed the experiments: TH KA. Performed the experiments: TH KA. Analyzed the data: NK TM HTI KY. Wrote the paper: TH KA HTI NK TM.