About the Authors

Minzhe Guo

Affiliations The Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Electrical Engineering and Computing Systems, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio, United States of America

Hui Wang

Affiliation The Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

S. Steven Potter

Affiliation Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

Jeffrey A. Whitsett

Affiliation The Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

Yan Xu

yan.xu@cchmc.org

Affiliations The Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and performed the single cell experiments: SSP JAW. Helped generate the lung single cell data: SSP JAW. Conceived and designed the analytic pipeline: YX MG. Analyzed the data: MG HW YX. Developed and implemented R code: MG. Contributed to the writing of the manuscript: MG YX JAW