Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features

Hirenkumar K. Makadia; James S. Schwaber; Rajanikanth Vadigepalli

doi:10.1371/journal.pcbi.1004563

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Open Access

Peer-reviewed

Research Article

Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features

Hirenkumar K. Makadia,

Affiliation Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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James S. Schwaber,

Affiliation Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Rajanikanth Vadigepalli

* E-mail: Rajanikanth.Vadigepalli@jefferson.edu

Affiliation Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯

Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features

Hirenkumar K. Makadia,
James S. Schwaber,
Rajanikanth Vadigepalli

Published: October 22, 2015
https://doi.org/10.1371/journal.pcbi.1004563

About the Authors

Hirenkumar K. Makadia

Affiliation Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

James S. Schwaber

Rajanikanth Vadigepalli

* E-mail: Rajanikanth.Vadigepalli@jefferson.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HKM RV. Performed the experiments: HKM. Analyzed the data: HKM RV. Contributed reagents/materials/analysis tools: HKM RV. Wrote the paper: HKM JSS RV. Edited the manuscript: HKM JSS RV.

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ERK signaling cascade
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Signaling networks
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Transcription factors
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Gene expression
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Immediate early genes
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Transcriptional control
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Network motifs
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