About the Authors

Naiqian Zhang

Contributed equally to this work with: Naiqian Zhang, Haiyun Wang

Affiliation Department of Mathematics, Shanghai Normal University, Shanghai, China

Haiyun Wang

Contributed equally to this work with: Naiqian Zhang, Haiyun Wang

Affiliation Department of Bioinformatics, School of Life Science and Technology, Tongji University, Shanghai, China

Yun Fang

Affiliation Department of Mathematics, Shanghai Normal University, Shanghai, China

Jun Wang

jwang@shnu.edu.cn (JW); xqzheng@shnu.edu.cn (XZ); xsliu@jimmy.harvard.edu (XSL)

Affiliation Department of Mathematics, Shanghai Normal University, Shanghai, China

Xiaoqi Zheng

jwang@shnu.edu.cn (JW); xqzheng@shnu.edu.cn (XZ); xsliu@jimmy.harvard.edu (XSL)

Affiliation Department of Mathematics, Shanghai Normal University, Shanghai, China

X. Shirley Liu

jwang@shnu.edu.cn (JW); xqzheng@shnu.edu.cn (XZ); xsliu@jimmy.harvard.edu (XSL)

Affiliations Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard School of Public Health, Boston, Massachusetts, United States of America, Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XSL XZ. Performed the experiments: XZ NZ JW. Analyzed the data: NZ HW YF. Contributed reagents/materials/analysis tools: NZ. Wrote the paper: XSL XZ NZ.