Manifold Based Optimization for Single-Cell 3D Genome Reconstruction

Jonas Paulsen; Odin Gramstad; Philippe Collas

doi:10.1371/journal.pcbi.1004396

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Open Access

Peer-reviewed

Research Article

Manifold Based Optimization for Single-Cell 3D Genome Reconstruction

Jonas Paulsen ,

Contributed equally to this work with: Jonas Paulsen, Odin Gramstad

* E-mail: jonaspau@medisin.uio.no

Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, and Norwegian Center for Stem Cell Research, University of Oslo, 0317 Oslo, Norway
⨯
Odin Gramstad ,

Contributed equally to this work with: Jonas Paulsen, Odin Gramstad

Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, and Norwegian Center for Stem Cell Research, University of Oslo, 0317 Oslo, Norway
⨯
Philippe Collas

Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, and Norwegian Center for Stem Cell Research, University of Oslo, 0317 Oslo, Norway
⨯

Manifold Based Optimization for Single-Cell 3D Genome Reconstruction

Jonas Paulsen,
Odin Gramstad,
Philippe Collas

Published: August 11, 2015
https://doi.org/10.1371/journal.pcbi.1004396

About the Authors

Jonas Paulsen

Contributed equally to this work with: Jonas Paulsen, Odin Gramstad

* E-mail: jonaspau@medisin.uio.no

Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, and Norwegian Center for Stem Cell Research, University of Oslo, 0317 Oslo, Norway

Odin Gramstad

Contributed equally to this work with: Jonas Paulsen, Odin Gramstad

Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, and Norwegian Center for Stem Cell Research, University of Oslo, 0317 Oslo, Norway

Philippe Collas

Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, and Norwegian Center for Stem Cell Research, University of Oslo, 0317 Oslo, Norway

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JP OG PC. Performed the experiments: OG. Analyzed the data: JP. Contributed reagents/materials/analysis tools: JP OG. Wrote the paper: JP OG PC.

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Chromosome structure and function
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Chromosome mapping
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X chromosomes
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Genomics
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Structural genomics
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Manifolds
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Optimization
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Mammalian genomics
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