About the Authors

Alexey A. Gritsenko

Affiliations The Delft Bioinformatics Lab, Department of Intelligent Systems, Delft University of Technology, Delft, The Netherlands, Platform Green Synthetic Biology, Delft, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Delft, The Netherlands

Marc Hulsman

Affiliation The Delft Bioinformatics Lab, Department of Intelligent Systems, Delft University of Technology, Delft, The Netherlands

Marcel J. T. Reinders

Affiliations The Delft Bioinformatics Lab, Department of Intelligent Systems, Delft University of Technology, Delft, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Delft, The Netherlands

Dick de Ridder

dick.deridder@wur.nl

Affiliations The Delft Bioinformatics Lab, Department of Intelligent Systems, Delft University of Technology, Delft, The Netherlands, Platform Green Synthetic Biology, Delft, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Delft, The Netherlands, Bioinformatics Group, Wageningen University, Wageningen, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AAG DdR. Analyzed the data: AAG. Wrote the paper: AAG MH MJTR DdR. Designed simulation algorithm: AAG MH.