About the Authors

Stepan Tymoshenko

Affiliations Laboratory of Computational Systems Biotechnology, École Polytechnique Fédérale de Lausanne, EPFL, Lausanne, Switzerland, Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, CMU, Geneva, Switzerland, Swiss Institute of Bioinformatics, Quartier Sorge, Batiment Genopode, Lausanne, Switzerland

Rebecca D. Oppenheim

Affiliation Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, CMU, Geneva, Switzerland

Rasmus Agren

Current address: Novo Nordisk A/S, Bagsvaerd, Denmark

Affiliation Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

Jens Nielsen

Affiliation Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

Dominique Soldati-Favre

Dominique.Soldati-Favre@unige.ch (DSF); Vassily.Hatzimanikatis@epfl.ch (VH)

Affiliation Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, CMU, Geneva, Switzerland

Vassily Hatzimanikatis

Dominique.Soldati-Favre@unige.ch (DSF); Vassily.Hatzimanikatis@epfl.ch (VH)

Affiliations Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, CMU, Geneva, Switzerland, Swiss Institute of Bioinformatics, Quartier Sorge, Batiment Genopode, Lausanne, Switzerland

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VH DSF. Analyzed the data: ST RDO DSF VH. Contributed reagents/materials/analysis tools: DSF RA JN VH. Wrote the paper: ST RDO DSF RA JN VH. Curated the model: ST RDO DSF RA JN VH Performed model reconstruction: ST Generated and characterized the transgenic parasites and analyzed the phenotypes: RDO.