About the Authors

Katja N. Rybakova

Current address: Systems Biology Ireland, University College Dublin, Dublin, Ireland

‡ These authors share first authorship on this work.

Affiliation Molecular Cell Physiology, VU University Amsterdam, Amsterdam, The Netherlands

Frank J. Bruggeman

‡ These authors share first authorship on this work.

Affiliation Systems Bioinformatics, VU University Amsterdam, Amsterdam, The Netherlands

Aleksandra Tomaszewska

Affiliation School of Medicine, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland

Martijn J. Moné

Affiliation Molecular Cell Physiology, VU University Amsterdam, Amsterdam, The Netherlands

Carsten Carlberg

Affiliation School of Medicine, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland

Hans V. Westerhoff

H.V.Westerhoff@vu.nl

Affiliations Molecular Cell Physiology, VU University Amsterdam, Amsterdam, The Netherlands, Manchester Centre for Integrative Systems Biology, University of Manchester, Manchester, United Kingdom, Synthetic Systems Biology, Netherlands Institute for Systems Biology, University of Amsterdam, Amsterdam, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Wrote the paper: KNR FJB HVW. Collection and analysis of the literature data: AT MJM CC. Model definition: KNR FJB HVW. Model implementation, simulation and analysis: KNR. Analytical derivations: FJB HVW.