About the Authors

James Lu

james.lu.jl1@roche.com

Affiliation F. Hoffmann-La Roche AG, pRED, Pharma Research & Early Development, Clinical Pharmacology, Basel, Switzerland

Katrin Hübner

Affiliation BioQuant, University of Heidelberg, Heidelberg, Germany

M. Nazeem Nanjee

Affiliation Division of Cardiovascular Genetics, University of Utah, Salt Lake City, Utah, United States of America

Eliot A. Brinton

Affiliation Utah Foundation for Biomedical Research, Salt Lake City, Utah, United States of America

Norman A. Mazer

Affiliation F. Hoffmann-La Roche AG, pRED, Pharma Research & Early Development, Clinical Pharmacology, Basel, Switzerland

Competing Interests

I have read the journal's policy and have the following conflicts: JL and NAM are employees of F. Hoffmann-La Roche; JL and NAM have stock ownership of F. Hoffmann-La Roche. KH, MNN and EAB declare no competing interest.

Author Contributions

Analyzed the data: JL NAM. Contributed reagents/materials/analysis tools: JL NAM. Wrote the paper: JL KH MNN EAB NAM.