VarWalker: Personalized Mutation Network Analysis of Putative Cancer Genes from Next-Generation Sequencing Data

Peilin Jia; Zhongming Zhao

doi:10.1371/journal.pcbi.1003460

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Open Access

Peer-reviewed

Research Article

VarWalker: Personalized Mutation Network Analysis of Putative Cancer Genes from Next-Generation Sequencing Data

Peilin Jia,

Affiliations Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Zhongming Zhao

* E-mail: zhongming.zhao@vanderbilt.edu

Affiliations Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯

VarWalker: Personalized Mutation Network Analysis of Putative Cancer Genes from Next-Generation Sequencing Data

Peilin Jia,
Zhongming Zhao

Published: February 6, 2014
https://doi.org/10.1371/journal.pcbi.1003460

About the Authors

Peilin Jia

Zhongming Zhao

* E-mail: zhongming.zhao@vanderbilt.edu

Affiliations Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PJ ZZ. Performed the experiments: PJ ZZ. Analyzed the data: PJ ZZ. Contributed reagents/materials/analysis tools: PJ ZZ. Wrote the paper: PJ ZZ.

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Genetic networks
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Skin tumors
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Mutation
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Protein interaction networks
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Melanoma
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Lung and intrathoracic tumors
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Mutation detection
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Adenocarcinoma of the lung
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