Epigenetics Decouples Mutational from Environmental Robustness. Did It Also Facilitate Multicellularity?

Saurabh Gombar; Thomas MacCarthy; Aviv Bergman

doi:10.1371/journal.pcbi.1003450

Loading metrics

Open Access

Peer-reviewed

Research Article

Epigenetics Decouples Mutational from Environmental Robustness. Did It Also Facilitate Multicellularity?

Saurabh Gombar ,

Contributed equally to this work with: Saurabh Gombar, Thomas MacCarthy

Affiliation Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America
⨯
Thomas MacCarthy ,

Contributed equally to this work with: Saurabh Gombar, Thomas MacCarthy

Affiliations Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America, Department of Applied Mathematics and Statistics, State University of New York, Stony Brook, New York, United States of America
⨯
Aviv Bergman

* E-mail: aviv.bergman@einstein.yu.edu

Affiliation Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America
⨯

Epigenetics Decouples Mutational from Environmental Robustness. Did It Also Facilitate Multicellularity?

Saurabh Gombar,
Thomas MacCarthy,
Aviv Bergman

Published: March 6, 2014
https://doi.org/10.1371/journal.pcbi.1003450

About the Authors

Saurabh Gombar

Contributed equally to this work with: Saurabh Gombar, Thomas MacCarthy

Affiliation Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America

Thomas MacCarthy

Contributed equally to this work with: Saurabh Gombar, Thomas MacCarthy

Affiliations Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America, Department of Applied Mathematics and Statistics, State University of New York, Stony Brook, New York, United States of America

Aviv Bergman

* E-mail: aviv.bergman@einstein.yu.edu

Affiliation Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SG TM AB. Performed the experiments: SG TM AB. Analyzed the data: SG TM AB. Contributed reagents/materials/analysis tools: SG TM. Wrote the paper: SG TM AB.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Epigenetics
Is the Subject Area "Epigenetics" applicable to this article?

Thanks for your feedback.
Cell differentiation
Is the Subject Area "Cell differentiation" applicable to this article?

Thanks for your feedback.
Evolutionary developmental biology
Is the Subject Area "Evolutionary developmental biology" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Gene regulatory networks
Is the Subject Area "Gene regulatory networks" applicable to this article?

Thanks for your feedback.
Evolutionary genetics
Is the Subject Area "Evolutionary genetics" applicable to this article?

Thanks for your feedback.
Organismal evolution
Is the Subject Area "Organismal evolution" applicable to this article?

Thanks for your feedback.
Genetic networks
Is the Subject Area "Genetic networks" applicable to this article?

Thanks for your feedback.