About the Authors

Eduard J. Kerkhoven

Contributed equally to this work with: Eduard J. Kerkhoven, Fiona Achcar

Affiliations Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation and Glasgow Polyomics, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Systems and Synthetic Biology Group, Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

Fiona Achcar

Contributed equally to this work with: Eduard J. Kerkhoven, Fiona Achcar

Affiliations Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands

Vincent P. Alibu

Current address: Department of Veterinary Parasitology and Microbiology, Faculty of Science, Makerere University, Kampala, Uganda.

Affiliation Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation and Glasgow Polyomics, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Richard J. Burchmore

Affiliation Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation and Glasgow Polyomics, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Ian H. Gilbert

Affiliation Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom

Maciej Trybiło

Affiliation School of Information Systems, Computing and Mathematics, Brunel University, Uxbridge, United Kingdom

Nicole N. Driessen

Current address: Department of Parasitology, Leiden University Medical Center, Leiden, the Netherlands.

Affiliation Department of Molecular Cell Physiology, Faculty of Earth and Life Sciences, VU University Amsterdam, Amsterdam, the Netherlands

David Gilbert

Affiliation School of Information Systems, Computing and Mathematics, Brunel University, Uxbridge, United Kingdom

Rainer Breitling

rainer.breitling@manchester.ac.uk (RB); b.m.bakker@umcg.nl (BMB); michael.barrett@glasgow.ac.uk (MPB)

Affiliation Faculty of Life Sciences, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom

Barbara M. Bakker

rainer.breitling@manchester.ac.uk (RB); b.m.bakker@umcg.nl (BMB); michael.barrett@glasgow.ac.uk (MPB)

Affiliations Department of Molecular Cell Physiology, Faculty of Earth and Life Sciences, VU University Amsterdam, Amsterdam, the Netherlands, Department of Pediatrics and Systems Biology Centre for Energy Metabolism and Ageing, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

Michael P. Barrett

rainer.breitling@manchester.ac.uk (RB); b.m.bakker@umcg.nl (BMB); michael.barrett@glasgow.ac.uk (MPB)

Affiliation Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation and Glasgow Polyomics, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EJK FA RJB IHG DG RB BMB MPB. Performed the experiments: EJK FA VPA MT NND. Analyzed the data: EJK FA VPA MT NND. Contributed reagents/materials/analysis tools: RJB. Wrote the paper: EJK FA RB BMB MPB.