Metabolic Constraint-Based Refinement of Transcriptional Regulatory Networks

Sriram Chandrasekaran; Nathan D. Price

doi:10.1371/journal.pcbi.1003370

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Open Access

Peer-reviewed

Research Article

Metabolic Constraint-Based Refinement of Transcriptional Regulatory Networks

Sriram Chandrasekaran,

Current address: Faculty of Arts and Sciences (FAS) Center for Systems Biology, Harvard Society of Fellows, Harvard University, Cambridge, Massachusetts, United States of America.

Affiliations Institute for Systems Biology, Seattle, Washington, United States of America, Center for Biophysics and Computational Biology, University of Illinois, Urbana-Champaign, Illinois, United States of America
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Nathan D. Price

* E-mail: nprice@systemsbiology.org

Affiliations Institute for Systems Biology, Seattle, Washington, United States of America, Center for Biophysics and Computational Biology, University of Illinois, Urbana-Champaign, Illinois, United States of America
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Metabolic Constraint-Based Refinement of Transcriptional Regulatory Networks

Sriram Chandrasekaran,
Nathan D. Price

Published: December 5, 2013
https://doi.org/10.1371/journal.pcbi.1003370

About the Authors

Sriram Chandrasekaran

Current address: Faculty of Arts and Sciences (FAS) Center for Systems Biology, Harvard Society of Fellows, Harvard University, Cambridge, Massachusetts, United States of America.

Affiliations Institute for Systems Biology, Seattle, Washington, United States of America, Center for Biophysics and Computational Biology, University of Illinois, Urbana-Champaign, Illinois, United States of America

Nathan D. Price

* E-mail: nprice@systemsbiology.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SC NDP. Performed the experiments: SC. Analyzed the data: SC. Wrote the paper: SC NDP.

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Metabolic networks
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Gene expression
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Network analysis
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Genetic networks
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Transcriptional control
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Gene regulatory networks
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Phenotypes
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Regulatory networks
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