Understanding the Connection between Epigenetic DNA Methylation and Nucleosome Positioning from Computer Simulations

Guillem Portella; Federica Battistini; Modesto Orozco

doi:10.1371/journal.pcbi.1003354

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Open Access

Peer-reviewed

Research Article

Understanding the Connection between Epigenetic DNA Methylation and Nucleosome Positioning from Computer Simulations

Guillem Portella ,

Contributed equally to this work with: Guillem Portella, Federica Battistini

Affiliations Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain, Joint IRB-BSC Program in Computational Biology, Barcelona, Spain
⨯
Federica Battistini ,

Contributed equally to this work with: Guillem Portella, Federica Battistini

Affiliations Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain, Joint IRB-BSC Program in Computational Biology, Barcelona, Spain
⨯
Modesto Orozco

* E-mail: modesto.orozco@irbbarcelona.org

Affiliations Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain, Joint IRB-BSC Program in Computational Biology, Barcelona, Spain, Departament de Bioquímica i Biologia Molecular, Universitat de Barcelona, Barcelona, Spain
⨯

Understanding the Connection between Epigenetic DNA Methylation and Nucleosome Positioning from Computer Simulations

Guillem Portella,
Federica Battistini,
Modesto Orozco

Published: November 21, 2013
https://doi.org/10.1371/journal.pcbi.1003354

About the Authors

Guillem Portella

Contributed equally to this work with: Guillem Portella, Federica Battistini

Affiliations Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain, Joint IRB-BSC Program in Computational Biology, Barcelona, Spain

Federica Battistini

Contributed equally to this work with: Guillem Portella, Federica Battistini

Affiliations Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain, Joint IRB-BSC Program in Computational Biology, Barcelona, Spain

Modesto Orozco

* E-mail: modesto.orozco@irbbarcelona.org

Affiliations Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain, Joint IRB-BSC Program in Computational Biology, Barcelona, Spain, Departament de Bioquímica i Biologia Molecular, Universitat de Barcelona, Barcelona, Spain

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GP FB MO. Performed the experiments: GP FB. Analyzed the data: GP FB MO. Wrote the paper: GP FB MO.

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DNA methylation
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Nucleosomes
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Histones
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Free energy
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Methylation
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Elasticity
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Molecular dynamics
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Cytosine
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