Versatility and Invariance in the Evolution of Homologous Heteromeric Interfaces

Jessica Andreani; Guilhem Faure; Raphaël Guerois

doi:10.1371/journal.pcbi.1002677

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Open Access

Peer-reviewed

Research Article

Versatility and Invariance in the Evolution of Homologous Heteromeric Interfaces

Jessica Andreani,

Affiliations CEA, iBiTecS, Service de Bioenergetique Biologie Structurale et Mecanismes (SB2SM), Laboratoire de Biologie Structurale et Radiobiologie (LBSR), Gif sur Yvette, France, CNRS, UMR 8221, Gif sur Yvette, France, Université Paris Sud, UMR 8221, Orsay, France
⨯
Guilhem Faure,

Affiliations CEA, iBiTecS, Service de Bioenergetique Biologie Structurale et Mecanismes (SB2SM), Laboratoire de Biologie Structurale et Radiobiologie (LBSR), Gif sur Yvette, France, CNRS, UMR 8221, Gif sur Yvette, France, Université Paris Sud, UMR 8221, Orsay, France
⨯
Raphaël Guerois

* E-mail: guerois@cea.fr

Affiliations CEA, iBiTecS, Service de Bioenergetique Biologie Structurale et Mecanismes (SB2SM), Laboratoire de Biologie Structurale et Radiobiologie (LBSR), Gif sur Yvette, France, CNRS, UMR 8221, Gif sur Yvette, France, Université Paris Sud, UMR 8221, Orsay, France
⨯

Versatility and Invariance in the Evolution of Homologous Heteromeric Interfaces

Jessica Andreani,
Guilhem Faure,
Raphaël Guerois

Published: August 30, 2012
https://doi.org/10.1371/journal.pcbi.1002677

About the Authors

Jessica Andreani

Affiliations CEA, iBiTecS, Service de Bioenergetique Biologie Structurale et Mecanismes (SB2SM), Laboratoire de Biologie Structurale et Radiobiologie (LBSR), Gif sur Yvette, France, CNRS, UMR 8221, Gif sur Yvette, France, Université Paris Sud, UMR 8221, Orsay, France

Guilhem Faure

Raphaël Guerois

* E-mail: guerois@cea.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JA RG. Performed the experiments: JA GF. Analyzed the data: JA GF RG. Wrote the paper: JA RG.

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Salt bridges
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Sequence alignment
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Hydrogen bonding
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Molecular evolution
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Evolutionary rate
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Monomers
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Protein complexes
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Protein-protein interactions
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