About the Authors
- Jun Zhu
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Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman
Affiliation Rosetta Inpharmatics, Seattle, Washington, United States of America
- Matthew C Wiener
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Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman
Affiliation Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America
- Chunsheng Zhang
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Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman
Affiliation Rosetta Inpharmatics, Seattle, Washington, United States of America
- Arthur Fridman
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Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman
Affiliation Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America
- Eric Minch
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Affiliation Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America
- Pek Y Lum
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Affiliation Rosetta Inpharmatics, Seattle, Washington, United States of America
- Jeffrey R Sachs
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Affiliation Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America
- Eric E Schadt
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*To whom correspondence should be addressed. E-mail: Eric_Schadt@merck.com
Affiliation Rosetta Inpharmatics, Seattle, Washington, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
JZ, MCW, CZ, AF, EM, PYL, JRS, and EES conceived the idea. JZ, CZ, AF, and JRS designed the simulation. MCW, AF, EM, and JRS designed the evaluation. JZ, AF, CZ, and JRS were responsible for genetic and gene expression data simulation. JZ, CZ, and AF were responsible for network reconstruction. PYL and JRS coordinated the project. All authors contributed to writing the paper.