About the Authors
- Ji Lee
-
Affiliations Department of Computational Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Bioengineering, Pennsylvania State University, University Park, Pennsylvania, United States of America
- Zhihua Li
-
Affiliation Department of Computational Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
- Rachel Brower-Sinning
-
Affiliation Department of Computational Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
- Bino John
-
*To whom correspondence should be addressed. E-mail: john@johnlab.org
Affiliations Department of Computational Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
JL implemented the K-Factor algorithm in Java, generated results, and contributed to writing the manuscript. ZL analyzed the core results and computationally identified specific CRMs. RBS was involved in benchmarking the performance of K-Factor. BJ conceived the project, designed and implemented the underlying methods and datasets, generated results, wrote the manuscript, and supervised the project.