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Open Access
Peer-reviewed
Research Article
DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist
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Michel Thépaut ,
Contributed equally to this work with: Michel Thépaut, Joanna Luczkowiak
Roles Investigation, Visualization
Affiliation Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble, France
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Joanna Luczkowiak ,
Contributed equally to this work with: Michel Thépaut, Joanna Luczkowiak
Roles Investigation, Visualization
Affiliation Instituto de Investigación Hospital Universitario 12 de Octubre (imas12), Universidad Complutense School of Medicine, Madrid, Spain
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Corinne Vivès,
Roles Investigation, Visualization
Affiliation Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble, France
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Nuria Labiod,
Roles Investigation
Affiliation Instituto de Investigación Hospital Universitario 12 de Octubre (imas12), Universidad Complutense School of Medicine, Madrid, Spain
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Isabelle Bally,
Roles Resources
Affiliation Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble, France
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Fátima Lasala,
Roles Investigation
Affiliation Instituto de Investigación Hospital Universitario 12 de Octubre (imas12), Universidad Complutense School of Medicine, Madrid, Spain
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Yasmina Grimoire,
Roles Resources
Affiliation Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble, France
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Daphna Fenel,
Roles Investigation
Affiliation Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble, France
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Sara Sattin,
Roles Writing – review & editing
Affiliation Universita`degli Studi di Milano, Dipartimento di Chimica, Milano, Italy
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Nicole Thielens,
Roles Resources
Affiliation Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble, France
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Guy Schoehn,
Roles Resources, Visualization
Affiliation Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble, France
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Anna Bernardi,
Roles Resources, Supervision, Writing – review & editing
Affiliation Universita`degli Studi di Milano, Dipartimento di Chimica, Milano, Italy
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Rafael Delgado ,
Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
* E-mail: rafael.delgado@salud.madrid.org (RD); franck.fieschi@ibs.fr (FF)
Affiliation Instituto de Investigación Hospital Universitario 12 de Octubre (imas12), Universidad Complutense School of Medicine, Madrid, Spain
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Franck Fieschi
Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
* E-mail: rafael.delgado@salud.madrid.org (RD); franck.fieschi@ibs.fr (FF)
Affiliation Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble, France
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DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist
- Michel Thépaut,
- Joanna Luczkowiak,
- Corinne Vivès,
- Nuria Labiod,
- Isabelle Bally,
- Fátima Lasala,
- Yasmina Grimoire,
- Daphna Fenel,
- Sara Sattin,
- Nicole Thielens
- Published: May 20, 2021
- https://doi.org/10.1371/journal.ppat.1009576