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Open Access
Peer-reviewed
Research Article
Evaluation of low-dose aspirin in the prevention of recurrent spontaneous preterm labour (the APRIL study): A multicentre, randomised, double-blinded, placebo-controlled trial
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Anadeijda J. E. M. C. Landman ,
Roles Data curation, Formal analysis, Investigation, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: a.landman@amsterdamumc.nl
Affiliation Department of Obstetrics and Gynaecology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands
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Marjon A. de Boer,
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands
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Laura Visser,
Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands
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Tobias A. J. Nijman,
Roles Conceptualization, Funding acquisition, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Haaglanden Medical Centre, Den Haag, the Netherlands
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Marieke A. C. Hemels,
Roles Conceptualization, Methodology, Writing – review & editing
Affiliation Department of Neonatal Intensive Care, Isala, Zwolle, the Netherlands
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Christiana N. Naaktgeboren,
Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Amsterdam UMC, University of Amsterdam, Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands
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Marijke C. van der Weide,
Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Amsterdam UMC, University of Amsterdam, Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands
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Ben W. Mol,
Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing
Affiliations Department of Obstetrics and Gynaecology, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia, Aberdeen Centre for Women’s Health Research, University of Aberdeen Aberdeen, United Kingdom
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Judith O. E. H. van Laar,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Máxima Medical Centre, Veldhoven, the Netherlands
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Dimitri N. M. Papatsonis,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Amphia Hospital, Breda, the Netherlands
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Mireille N. Bekker,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, University Medical Centre Utrecht, Utrecht, the Netherlands
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Joris van Drongelen,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, the Netherlands
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Mariëlle G. van Pampus,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, OLVG, Amsterdam, the Netherlands
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Marieke Sueters,
Roles Data curation, Investigation, Writing – original draft, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Leiden University Medical Centre, Leiden, the Netherlands
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David P. van der Ham,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Martini Hospital, Groningen, the Netherlands
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J. Marko Sikkema,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Hospital Group Twente Almelo, Almelo, the Netherlands
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Joost J. Zwart,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Deventer Hospital, Deventer, the Netherlands
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Anjoke J. M. Huisjes,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Gelre Hospitals Apeldoorn, Apeldoorn, the Netherlands
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Marloes E. van Huizen,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Haga Hospital, Den Haag, the Netherlands
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Gunilla Kleiverda,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Flevo Hospital Almere, Almere, the Netherlands
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Janine Boon,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Diakonessenhuis, Utrecht, the Netherlands
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Maureen T. M. Franssen,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, University Medical Centre Groningen, Groningen, the Netherlands
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Wietske Hermes,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Haaglanden Medical Centre, Den Haag, the Netherlands
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Harry Visser,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Tergooi Hospitals, Hilversum, the Netherlands
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Christianne J. M. de Groot,
Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands
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Martijn A. Oudijk
Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, Amsterdam UMC, University of Amsterdam, Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands
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Evaluation of low-dose aspirin in the prevention of recurrent spontaneous preterm labour (the APRIL study): A multicentre, randomised, double-blinded, placebo-controlled trial
- Anadeijda J. E. M. C. Landman,
- Marjon A. de Boer,
- Laura Visser,
- Tobias A. J. Nijman,
- Marieke A. C. Hemels,
- Christiana N. Naaktgeboren,
- Marijke C. van der Weide,
- Ben W. Mol,
- Judith O. E. H. van Laar,
- Dimitri N. M. Papatsonis
- Published: February 1, 2022
- https://doi.org/10.1371/journal.pmed.1003892