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Zymogens

Sensitivity analysis of a reduced model of thrombosis under flow: Roles of Factor IX, Factor XI, and γ‘-Fibrin

Jason Chen, Scott L. Diamond

published 23 Nov 2021

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The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane

Chun-Che Tseng, Bailing Jia, Robert B. Barndt, Yang-Hong Dai, Yu Hsin Chen, Po-Wen A. Du, Jehng-Kang Wang, Hung-Jen Tang, Chen-Yong Lin, Michael D. Johnson

published 12 Feb 2020

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Coagulant activity of recombinant human factor VII produced by lentiviral human F7 gene transfer in immortalized hepatocyte-like cell line

Sarai Pongjantarasatian, Praguywan Kadegasem, Werasak Sasanakul, Khanit Sa-ngiamsuntorn, Suparerk Borwornpinyo, Nongnuch Sirachainan, Ampaiwan Chuansumrit, Pansakorn Tanratana, Suradej Hongeng

published 05 Aug 2019

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Activity and post-prandial regulation of digestive enzyme activity along the Pacific hagfish (Eptatretus stoutii) alimentary canal

Alyssa M. Weinrauch, Christina M. Schaefer, Greg G. Goss

published 05 Apr 2019

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A local and global sensitivity analysis of a mathematical model of coagulation and platelet deposition under flow

Kathryn G. Link, Michael T. Stobb, Jorge Di Paola, Keith B. Neeves, Aaron L. Fogelson, Suzanne S. Sindi, Karin Leiderman

published 26 Jul 2018

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Crystal structures of human procathepsin H

Yue Hao, Whitney Purtha, Christa Cortesio, Huan Rui, Yan Gu, Hao Chen, E. Allen Sickmier, Paolo Manzanillo, Xin Huang

published 25 Jul 2018

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Cigarette toxin 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces experimental pancreatitis through α7 nicotinic acetylcholine receptors (nAChRs) in mice

A. A. Alahmari, B. Sreekumar, V. Patel, M. Ashat, M. Alexandre, A. K. Uduman, E. O. Akinbiyi, A. Ceplenski, C. A. Shugrue, T. R. Kolodecik, N. Tashkandi, S. W. Messenger, G. E. Groblewski, F. S. Gorelick, E. C. Thrower

published 05 Jun 2018

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Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy

Roman Szabo, Thomas H. Bugge

published 04 Apr 2018

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Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin

Shiao-Pieng Lee, Chen-Yu Kao, Shun-Cheng Chang, Yi-Lin Chiu, Yen-Ju Chen, Ming-Hsing G. Chen, Chun-Chia Chang, Yu-Wen Lin, Chien-Ping Chiang, Jehng-Kang Wang, Chen-Yong Lin, Michael D. Johnson

published 13 Feb 2018

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Involvement of Arabidopsis thaliana endoplasmic reticulum KDEL-tailed cysteine endopeptidase 1 (AtCEP1) in powdery mildew-induced and AtCPR5-controlled cell death

Timo Höwing, Marcel Dann, Caroline Hoefle, Ralph Hückelhoven, Christine Gietl

published 28 Aug 2017

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Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity

Chun-Che Tseng, Bailing Jia, Robert Barndt, Yayun Gu, Chien-Yu Chen, I-Chu Tseng, Sheng-Fang Su, Jehng-Kang Wang, Michael D. Johnson, Chen-Yong Lin

published 22 Aug 2017

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Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2

Frank Shiao, Li-Ching O. Liu, Nanxi Huang, Ying-Jung J. Lai, Robert J. Barndt, Chun-Che Tseng, Jehng-Kang Wang, Bailing Jia, Michael D. Johnson, Chen-Yong Lin

published 26 Jan 2017

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Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner

Hui Chen Su, Yan A. Liang, Ying-Jung J. Lai, Yi-Lin Chiu, Robert B. Barndt, Frank Shiao, Hsiang-Hua D. Chang, Dajun D. Lu, Nanxi Huang, Chun-Che Tseng, Jehng-Kang Wang, Ming-Shyue Lee, Michael D. Johnson, Shih-Ming Huang, Chen-Yong Lin

published 09 Dec 2016

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