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Viral entry

Amino acid residues 655 and 969 in the spike protein of Omicron subvariant BA.1 control use of TMPRSS2 versus Cathepsin L dependent entry pathways and cell tropism

Cheila Rocha, Prerna Arora, Lu Zhang, Anzhalika Sidarovich, Luise Graichen, Anna-Sophie Moldenhauer, Stefan Pöhlmann, Markus Hoffmann

published 14 Aug 2025

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Spike substitutions E484D, P812R and Q954H mediate ACE2-independent entry of SARS-CoV-2 across different cell lines

Greta Vizgirda, Alexander P. Underwood, Ulrik Fahnøe, Nina Weis, Santseharay Ramirez, Jens Bukh

published 01 Aug 2025

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Different SARS-CoV-2 variants inhibited by RRM designed peptide

Uros Krapez, Urska Kuhar, Petra Šenica, Brigita Slavec, Drasko Cosic, Ivan Loncarevic, Sandra Janezic, Irena Cosic

published 22 Jul 2025

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The NADC30-like PRRSV activates the integrin αV subunit to facilitate its entry into Marc-145 cells

Chunlin Li, Jin Cui, Hui Zheng, Zhou Sha, Rong Wei, Rui Wu, Bo Ni

published 27 Mar 2025

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Pregnancy-induced differential expression of SARS-CoV-2 and influenza a viral entry factors in the lower respiratory tract

Tusar Giri, Santosh Panda, Arvind Palanisamy

published 12 Jul 2023

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Glycyrrhizin through liquorice intake modulates ACE2 and HMGB1 levels—A pilot study in healthy individuals with implications for COVID-19 and ARDS

Felix Buder, Simina-Ramona Selejan, Mathias Hohl, Michael Kindermann, Christian Herr, Philipp M. Lepper, Robert Bals, Bernd Salzberger, Felix Mahfoud, Michael Böhm

published 17 Oct 2022

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Bovine colostrum-derived antibodies against SARS-CoV-2 show great potential to serve as prophylactic agents

Kadri Kangro, Mihhail Kurašin, Kiira Gildemann, Eve Sankovski, Eva Žusinaite, Laura Sandra Lello, Raini Pert, Ants Kavak, Väino Poikalainen, Lembit Lepasalu, Marilin Kuusk, Robin Pau, Sander Piiskop, Siimu Rom, Ruth Oltjer, Kairi Tiirik, Karin Kogermann, Mario Plaas, Toomas Tiirats, Birgit Aasmäe, Mihkel Plaas, Karl Mumm, Dagni Krinka, Ene Talpsep, Meelis Kadaja, Joachim M. Gerhold, Anu Planken, Andres Tover, Andres Merits, Andres Männik, Mart Ustav Jr, Mart Ustav

published 10 Jun 2022

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Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction

Amit Mahindra, Gonzalo Tejeda, Mario Rossi, Omar Janha, Imogen Herbert, Caroline Morris, Danielle C. Morgan, Wendy Beattie, Augusto C. Montezano, Brian Hudson, Andrew B. Tobin, David Bhella, Rhian M. Touyz, Andrew G. Jamieson, George S. Baillie, Connor M. Blair

published 18 Nov 2021

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Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies

Claudia Pommerenke, Ulfert Rand, Cord C. Uphoff, Stefan Nagel, Margarete Zaborski, Vivien Hauer, Maren Kaufmann, Corinna Meyer, Sabine A. Denkmann, Peggy Riese, Kathrin Eschke, Yeonsu Kim, Zeljka Macak Safranko, Ivan-Christian Kurolt, Alemka Markotic, Luka Cicin-Sain, Laura Steenpass

published 02 Aug 2021

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Identification and evaluation of the inhibitory effect of Prunella vulgaris extract on SARS-coronavirus 2 virus entry

Zhujun Ao, Mable Chan, Maggie Jing Ouyang, Titus Abiola Olukitibi, Mona Mahmoudi, Darwyn Kobasa, Xiaojian Yao

published 09 Jun 2021

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Establishment of a well-characterized SARS-CoV-2 lentiviral pseudovirus neutralization assay using 293T cells with stable expression of ACE2 and TMPRSS2

Sabari Nath Neerukonda, Russell Vassell, Rachel Herrup, Shufeng Liu, Tony Wang, Kazuyo Takeda, Ye Yang, Tsai-Lien Lin, Wei Wang, Carol D. Weiss

published 10 Mar 2021

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Mathematical determination of the HIV-1 matrix shell structure and its impact on the biology of HIV-1

Weijie Sun, Eduardo Reyes-Serratos, David Barilla, Joy Ramielle L. Santos, Mattéa Bujold, Sean Graves, Marcelo Marcet-Palacios

published 12 Nov 2019

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Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins

Teresa Plegge, Martin Spiegel, Nadine Krüger, Inga Nehlmeier, Michael Winkler, Mariana González Hernández, Stefan Pöhlmann

published 11 Apr 2019

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