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Utrophin

Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy

Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, Onnik Agbulut, Arnaud Ferry

published 08 Mar 2024

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Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MHCK7.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effect on muscle strength

Paul T. Martin, Deborah A. Zygmunt, Anna Ashbrook, Sonia Hamilton, Davin Packer, Sharla M. Birch, Amanda K. Bettis, Cynthia J. Balog-Alvarez, Lee-Jae Guo, Peter P. Nghiem, Joe N. Kornegay

published 26 Mar 2021

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Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice

Antoine Boulanger Piette, Dounia Hamoudi, Laetitia Marcadet, Frédérique Kyomi Labelle, Rares Ovidiu David, Sabrina Bossé, Anteneh Argaw, Jérôme Frenette

published 07 Jun 2018

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Functional improvement of dystrophic muscle by repression of utrophin: let-7c interaction

Manoj K. Mishra, Emanuele Loro, Kasturi Sengupta, Steve D. Wilton, Tejvir S. Khurana

published 18 Oct 2017

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Safety, Tolerability, and Pharmacokinetics of SMT C1100, a 2-Arylbenzoxazole Utrophin Modulator, following Single- and Multiple-Dose Administration to Pediatric Patients with Duchenne Muscular Dystrophy

Valeria Ricotti, Stefan Spinty, Helen Roper, Imelda Hughes, Bina Tejura, Neil Robinson, Gary Layton, Kay Davies, Francesco Muntoni, Jonathon Tinsley

published 07 Apr 2016

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Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies

Narinder Janghra, Jennifer E. Morgan, Caroline A. Sewry, Francis X. Wilson, Kay E. Davies, Francesco Muntoni, Jonathon Tinsley

published 14 Mar 2016

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Cis-Acting Sequence Elements and Upstream Open Reading Frame in Mouse Utrophin-A 5'-UTR Repress Cap-Dependent Translation

Trinath Ghosh, Utpal Basu

published 31 Jul 2015

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Whole Body Periodic Acceleration Is an Effective Therapy to Ameliorate Muscular Dystrophy in mdx Mice

Francisco Altamirano, Claudio F. Perez, Min Liu, Jeffrey Widrick, Elisabeth R. Barton, Paul D. Allen, Jose A. Adams, Jose R. Lopez

published 02 Sep 2014

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Identification of New Dystroglycan Complexes in Skeletal Muscle

Eric K. Johnson, Bin Li, Jung Hae Yoon, Kevin M. Flanigan, Paul T. Martin, James Ervasti, Federica Montanaro

published 08 Aug 2013

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Regeneration of Soft Tissues Is Promoted by MMP1 Treatment after Digit Amputation in Mice

Xiaodong Mu, Ian Bellayr, Haiying Pan, Yohan Choi, Yong Li

published 18 Mar 2013

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The Tandem PH Domain-Containing Protein 2 (TAPP2) Regulates Chemokine-Induced Cytoskeletal Reorganization and Malignant B Cell Migration

Hongzhao Li, Sen Hou, Xun Wu, Saravanan Nandagopal, Francis Lin, Sam Kung, Aaron James Marshall

published 27 Feb 2013

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The Crystal Structures of Dystrophin and Utrophin Spectrin Repeats: Implications for Domain Boundaries

Muralidharan Muthu, Kylie A. Richardson, Andrew J. Sutherland-Smith

published 20 Jul 2012

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The Effects of Low Levels of Dystrophin on Mouse Muscle Function and Pathology

Maaike van Putten, Margriet Hulsker, Vishna Devi Nadarajah, Sandra H. van Heiningen, Ella van Huizen, Maarten van Iterson, Peter Admiraal, Tobias Messemaker, Johan T. den Dunnen, Peter A. C. 't Hoen, Annemieke Aartsma-Rus

published 16 Feb 2012

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