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Tumor suppressor genes

Integrated transcriptomic analysis reveals a CEBPB–DUSP1 axis driving tumor progression in colorectal cancer

Huarong Zhou, Lili Fang

published 18 Dec 2025

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Genomic discovery of EF-24 targets unveils antitumorigenic mechanisms in leukemia cells

Ajeet P. Singh, Noah Wax, James Duncan, Ana S. Fernandes, Jonathan L. Jacobs

published 23 Sep 2025

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The tumor suppressor FAT1 controls YAP/TAZ protein degradation and tumor cell proliferation through E3 ligase MIB2

Rui Li, Boris Strilic, Young-June Jin, Jingchen Shao, Yundong Peng, Lei Wang, Qi Quan, Zhiyong Wang, Johannes Graumann, J. Silvio Gutkind, Nina Wettschureck, Stefan Offermanns

published 06 Jun 2025

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CPI203, a BET inhibitor, down-regulates a consistent set of DNA synthesis genes across a wide array of glioblastoma lines

Matthew C. Garrett, Troy Carnwath, Rebecca Albano, Yonghua Zhuang, Catherine A. Behrmann, Merissa Pemberton, Farah Barakat, Robert Lober, Mark Hoeprich, Anthony Paravati, Marilyn Reed, Hailey Spry, Daniel Woo, Eric O’Brien, Brett VanCauwenbergh, John Perentesis, Rani Nasser, Mario Medvedovic, David R. Plas

published 16 May 2025

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FAM50A as a novel prognostic marker modulates the proliferation of colorectal cancer cells via CylinA2/CDK2 pathway

Longhai Li, Zhaoshuai Ji, Guangyun Li, Hao Gu, Yan Sun

published 25 Feb 2025

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Differential effect of plakoglobin in restoring the tumor suppressor activities of p53-R273H vs. p53-R175H mutants

Chu Shiun Lo, Parnian Alavi, Blessing Bassey-Archibong, Nadia Jahroudi, Manijeh Pasdar

published 03 Oct 2024

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The role of palbociclib on the alterations in CDKN2, CCNE1, E2F3, MDM2 expressions as target genes of miR-141

Mohammad Ali Baziyar, Arshad Hosseini, Farinush Jandel

published 08 Aug 2024

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Achillea fragrantissima (Forssk.) Sch.Bip instigates the ROS/FADD/c-PARP expression that triggers apoptosis in breast cancer cell (MCF-7)

Abdulrahman Alasmari

published 31 May 2024

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Intronic miR-6741-3p targets the oncogene SRSF3: Implications for oral squamous cell carcinoma pathogenesis

Dhanashree Anil More, Nivedita Singh, Radha Mishra, Harsha Pulakkat Muralidharan, Kodaganur Srinivas Gopinath, Champaka Gopal, Arun Kumar

published 23 May 2024

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Upregulation of LHPP by saRNA inhibited hepatocellular cancer cell proliferation and xenograft tumor growth

Chuan-Qian Bi, Tao Kang, Yu-Kang Qian, Moorim Kang, Xu-Hui Zeng, Long-Cheng Li

published 02 May 2024

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Pharmacological induction of translational readthrough of nonsense mutations in the retinoblastoma (RB1) gene

Mireia Palomar-Siles, Viktor Yurevych, Vladimir J. N. Bykov, Klas G. Wiman

published 02 Nov 2023

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Effect of miR-34a on the expression of clock and clock-controlled genes in DLD1 and Lovo human cancer cells with different backgrounds with respect to p53 functionality and 17β-estradiol-mediated regulation

Roman Moravčík, Soňa Olejárová, Jana Zlacká, Iveta Herichová

published 13 Oct 2023

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Epigenetic regulation in colorectal cancer: The susceptibility of microRNAs 145, 143 and 133b to DNA demethylation and histone deacetylase inhibitors

Aadilah Omar, Drishna Govan, Clement Penny

published 10 Aug 2023

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