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Tumor physiology

5-O-Methylvisammioside inhibits HMGB1-induced Angiogenesis of hepatocellular carcinoma through RAGE/MEK/ERK signaling pathway

Wenyue Hou, Ting Zou, Yichao Yan, Yaolong Zhuang, Shaomei Gao, Huijun Ju, Fei Yao, Qin Yuan, Liang Zhou, Guoqiang Liang, Xiudao Song, Lurong Zhang

published 05 May 2025

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Gold nanoparticle-enhanced radiotherapy: Dependence of the macroscopic dose enhancement on the microscopic localization of the nanoparticles within the tumor vasculature

C. A. Díaz-Galindo, H. M. Garnica-Garza

published 05 Jul 2024

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CAF-associated genes putatively representing distinct prognosis by in silico landscape of stromal components of colon cancer

Kota Okuno, Kyonosuke Ikemura, Riku Okamoto, Keiko Oki, Akiko Watanabe, Yu Kuroda, Mikiko Kidachi, Shiori Fujino, Yusuke Nie, Tadashi Higuchi, Motohiro Chuman, Marie Washio, Mikiko Sakuraya, Masahiro Niihara, Koshi Kumagai, Takafumi Sangai, Yusuke Kumamoto, Takeshi Naitoh, Naoki Hiki, Keishi Yamashita

published 01 Apr 2024

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11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis

Callam T. Davidson, Eileen Miller, Morwenna Muir, John C. Dawson, Martin Lee, Stuart Aitken, Alan Serrels, Scott P. Webster, Natalie Z. M. Homer, Ruth Andrew, Valerie G. Brunton, Patrick W. F. Hadoke, Brian R. Walker

published 20 Mar 2023

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Investigating CXCR4 expression of tumor cells and the vascular compartment: A multimodal approach

Marta Braga, Chee Hau Leow, Javier Hernandez Gil, Jin H. Teh, Laurence Carroll, Nicholas J. Long, Meng-Xing Tang, Eric O. Aboagye

published 18 Nov 2021

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A randomized phase I study comparing the pharmacokinetics of a bevacizumab (HD204) biosimilar to European Union- and United States of America-sourced bevacizumab

Martin Demarchi, Pierre Coliat, Philippe Barthelemy, Roland Schott, Meher BenAbdelghani, Michael Kim, Jocelyn Chung Shii Hii, Peggy Feyaerts, Felicia Rui Xia Ang, Marie Paule Derde, Filip Deforce, Thierry Petit, Chris Schwabe, Chris Wynne, Lisa Soyeon Park, Xavier Pivot

published 23 Sep 2021

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The cancer angiogenesis co-culture assay: In vitro quantification of the angiogenic potential of tumoroids

Sarah Line Bring Truelsen, Nabi Mousavi, Haoche Wei, Lucy Harvey, Rikke Stausholm, Erik Spillum, Grith Hagel, Klaus Qvortrup, Ole Thastrup, Henrik Harling, Harry Mellor, Jacob Thastrup

published 07 Jul 2021

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A novel method of screening combinations of angiostatics identifies bevacizumab and temsirolimus as synergistic inhibitors of glioma-induced angiogenesis

Michael I. Dorrell, Heidi R. Kast-Woelbern, Ryan T. Botts, Stephen A. Bravo, Jacob R. Tremblay, Sarah Giles, Jessica F. Wada, MaryAnn Alexander, Eric Garcia, Gabriel Villegas, Caylor B. Booth, Kaitlyn J. Purington, Haylie M. Everett, Erik N. Siles, Michael Wheelock, Jordan A. Silva, Bridget M. Fortin, Connor A. Lowey, Allison L. Hale, Troy L. Kurz, Jack C. Rusing, Dawn M. Goral, Paul Thompson, Alec M. Johnson, Daniel J. Elson, Roujih Tadros, Charisa E. Gillette, Carley Coopwood, Amy L. Rausch, Jeffrey M. Snowbarger

published 02 Jun 2021

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Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature

Mark P. Labrecque, Lisha G. Brown, Ilsa M. Coleman, Holly M. Nguyen, Daniel W. Lin, Eva Corey, Peter S. Nelson, Colm Morrissey

published 20 Jan 2021

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Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model

Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Hiroki Nagase

published 27 Apr 2020

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A hybrid model of tumor growth and angiogenesis: In silico experiments

Caleb M. Phillips, Ernesto A. B. F. Lima, Ryan T. Woodall, Amy Brock, Thomas E. Yankeelov

published 10 Apr 2020

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The effect of human placental chorionic villi derived mesenchymal stem cell on triple-negative breast cancer hallmarks

Alaa T. Alshareeda, Emad Rakha, Ayidah Alghwainem, Bahauddeen Alrfaei, Batla Alsowayan, Abdullah Albugami, Abdullah M. Alsubayyil, Mohmed Abomraee, Nur Khatijah Mohd Zin

published 20 Nov 2018

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Angiogenic role of miR-20a in breast cancer

Gines Luengo-Gil, Enrique Gonzalez-Billalabeitia, Sergio Alejo Perez-Henarejos, Esther Navarro Manzano, Asuncion Chaves-Benito, Elena Garcia-Martinez, Elisa Garcia-Garre, Vicente Vicente, Francisco Ayala de la Peña

published 04 Apr 2018

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