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Tuberculosis drug discovery

A meta-proteomics approach using autopsy material from the pre-antibiotic era from patients with untreated pulmonary tuberculosis to identify proteins present in early lesions of post-primary tuberculosis

Beatrice Normann, Syeda Mariam Riaz, Lisbet Sviland, Tehmina Mustafa, Even Birkeland

published 01 Apr 2026

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Genotypic drug resistance and transmission clusters of Mycobacterium tuberculosis isolates among Ethiopian returnees from Saudi Arabia

Melaku Tilahun, Abay Atnafu, Tewodros Tariku Gebresilase, Muluye Abebe, Mekdes Alemu, Sebisib Neway, Taye Letta, Abiot Bezabeh, Tamiru Assefa, Kalkidan Melaku, Dawit Hailu Alemayehu, Shewki Moga, Abaysew Ayele, Maeruf Fetu, Bethlehem Adnew, Andargachew Mulu, Liya Wassie, Kidist Bobosha

published 16 Apr 2025

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Relationship between hospitalization from cannabis usage and pulmonary tuberculosis in Thailand from 2017 to 2022

Kemmapon Chumchuen, Wit Wichaidit, Virasakdi Chongsuvivatwong

published 05 Dec 2024

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Integrated virtual screening and MD simulation study to discover potential inhibitors of mycobacterial electron transfer flavoprotein oxidoreductase

Kaleem Arshad, Jahanzab Salim, Muhammad Ali Talat, Asifa Ashraf, Nazia Kanwal

published 15 Nov 2024

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Coping efforts made: Psychological burden of people living with tuberculosis due to social stigma in society. A qualitative phenomenology study

Abd Nasir, Intan Idiana Hassan, Anwar Ma’ruf, Novianto Edi Suharno, Sianiwati Goenharto, Cucuk Rahmadi Purwanto, Anestasia Pangestu Mei Tyas

published 30 Jul 2024

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Progress and challenges in achieving tuberculosis elimination in India by 2025: A systematic review and meta-analysis

Abhishek Padhi, Ashwini Agarwal, Mayuri Bhise, Anil Chaudhary, Krupal Joshi, C. D. S. Katoch

published 27 Mar 2024

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White plague among the “forgotten people” from the Barbaricum of the Carpathian Basin–Cases with tuberculosis from the Sarmatian-period (3^rd–4^th centuries CE) archaeological site of Hódmezővásárhely–Kenyere-ér, Bereczki-tanya (Hungary)

Olga Spekker, Attila Kiss P., Luca Kis, Kitty Király, Sándor Varga, Antónia Marcsik, Oszkár Schütz, Tibor Török, David R. Hunt, Balázs Tihanyi

published 10 Jan 2024

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Perceptions about and reasons for participation in research bronchoscopy in Uganda: A qualitative analysis

David Kaawa-Mafigiri, Mary Nsereko, Michael Odie, John L. Johnson

published 20 Oct 2023

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Phenotypic and genotypic drug susceptibility patterns of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Central and Southern Ethiopia

Melaku Tilahun, Teklu Wegayehu, Biniam Wondale, Tewdros Tariku Gebresilase, Tesfaye Gebreyohannes, Abraham Tekola, Mekdes Alemu, Sebsib Neway, Bethlehem Adnew, Maeruf Fetu Nassir, Yonas Kassahun, Abraham Aseffa, Kidist Bobosha

published 08 Sep 2023

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Differentially expressed transcript isoforms associate with resistance to tuberculin skin test and interferon gamma release assay conversion

Jason D. Simmons, R. Max Segnitz, Kimberly A. Dill-McFarland, Catherine M. Stein, Glenna J. Peterson, Harriet Mayanja-Kizza, W. Henry Boom, Thomas R. Hawn

published 14 Apr 2023

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In-vivo studies on Transitmycin, a potent Mycobacterium tuberculosis inhibitor

Rajesh Mondal, Azger Dusthackeer V. N., Palaniyandi Kannan, Amit Kumar Singh, Kannan Thiruvengadam, Radhakrishnan Manikkam, Shainaba A. S., Mahizhaveni Balasubramanian, Padmasini Elango, Sam Ebenezer Rajadas, Dinesh Bharadwaj, Gandarvakottai Senthilkumar Arumugam, Suresh Ganesan, Hemanth Kumar A. K., Manjula Singh, Shripad Patil, Jaleel U. C. A., Mukesh Doble, Balagurunathan R., Srikanth Prasad Tripathy, Vanaja Kumar

published 03 Mar 2023

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Shotgun proteomic profiling of dormant, ‘non-culturable’ Mycobacterium tuberculosis

Vadim Nikitushkin, Margarita Shleeva, Dmitry Loginov, Filip Dyčka F., Jan Sterba, Arseny Kaprelyants

published 09 Aug 2022

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Magnitude of Mycobacterium tuberculosis, drug resistance and associated factors among presumptive tuberculosis patients at St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia

Melkayehu Kassa, Kassu Desta, Rozina Ambachew, Zenebe Gebreyohannes, Alganesh Gebreyohanns, Nuhamen Zena, Misikir Amare, Betselot Zerihun, Melak Getu, Addisu Gize

published 01 Aug 2022

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