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Transactivation

The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries

Xuan Yu, John N. Stallone, Cristine L. Heaps, Guichun Han

published 23 Jan 2018

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An extract from date palm fruit (Phoenix dactylifera) acts as a co-agonist ligand for the nuclear receptor FXR and differentially modulates FXR target-gene expression in vitro

Emilia Alfaro-Viquez, Brent F. Roling, Christian G. Krueger, Charlene J. Rainey, Jess D. Reed, Marie-Louise Ricketts

published 02 Jan 2018

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Efficacy and safety of selective glucocorticoid receptor modulators in comparison to glucocorticoids in arthritis, a systematic review

M. Safy, M. J. H. de Hair, J. W. G. Jacobs, F. Buttgereit, M. C. Kraan, J. M. van Laar

published 21 Dec 2017

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Regulation of hepatic stellate cell proliferation and activation by glutamine metabolism

Jiang Li, Mohammed Ghazwani, Ke Liu, Yixian Huang, Na Chang, Jie Fan, Fengtian He, Liying Li, Shizhong Bu, Wen Xie, Xiaochao Ma, Song Li

published 10 Aug 2017

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Analysis of novel RUNX2 mutations in Chinese patients with cleidocranial dysplasia

Xianli Zhang, Yang Liu, Xiaozhe Wang, Xiangyu Sun, Chenying Zhang, Shuguo Zheng

published 24 Jul 2017

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RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells

Danielle Kamato, Venkata Vijayanand Bhaskarala, Nitin Mantri, Tae Gyu Oh, Dora Ling, Reearna Janke, Wenhua Zheng, Peter J Little, Narin Osman

published 18 Jul 2017

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FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25

Alexandra Rasnitsyn, Lance Doucette, Morteza Seifi, Tim Footz, Vincent Raymond, Michael A. Walter

published 02 Jun 2017

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Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists

Katrine Qvortrup, Jakob F. Jensen, Mikael S. Sørensen, Irene Kouskoumvekaki, Rasmus K. Petersen, Olivier Taboureau, Karsten Kristiansen, Thomas E. Nielsen

published 28 Feb 2017

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The 9aaTAD Is Exclusive Activation Domain in Gal4

Martin Piskacek, Marek Havelka, Martina Rezacova, Andrea Knight

published 05 Jan 2017

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Evolutionary and Functional Diversification of the Vitamin D Receptor-Lithocholic Acid Partnership

Erin M. Kollitz, Guozhu Zhang, Mary Beth Hawkins, G. Kerr Whitfield, David M. Reif, Seth W. Kullman

published 12 Dec 2016

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Endothelin B Receptors on Primary Chicken Müller Cells and the Human MIO-M1 Müller Cell Line Activate ERK Signaling via Transactivation of Epidermal Growth Factor Receptors

Mohammad Harun-Or-Rashid, Dardan Konjusha, Caridad Galindo-Romero, Finn Hallböök

published 08 Dec 2016

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Novel Nuclear Factor-KappaB Targeting Peptide Suppresses β-Amyloid Induced Inflammatory and Apoptotic Responses in Neuronal Cells

Mythily Srinivasan, Baindu Bayon, Nipun Chopra, Debomoy K. Lahiri

published 20 Oct 2016

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A Natural Mutation in Helix 5 of the Ligand Binding Domain of Glucocorticoid Receptor Enhances Receptor-Ligand Interaction

Henry Reyer, Siriluck Ponsuksili, Ellen Kanitz, Ralf Pöhland, Klaus Wimmers, Eduard Murani

published 13 Oct 2016

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