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Toxicology

Integrating bioactivity and molecular simulations to explore the pharmacological landscape of Lagerstroemia speciosa leaf extract

Md Shajedul Haque, Rubel Ahmad, Bidhan Chandra Sarkar, Manoshi Sana, Hasi Rani Saha, Niranjan Kumar Sana

published 29 Dec 2025

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Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

Chizuka Obara, Yohei Iizaka, Akari Mine, Yojiro Anzai, Masako Tada, Shinpei Yamaguchi

published 29 Dec 2025

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Heavy metal exposure and its impact on inflammatory ratios in minors: The mediating role of BMI

Xinpeng Li, Lu Han

published 29 Dec 2025

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Identification of new triazoloquinoxaline amine derivatives with potent modulatory effects against Toll-like receptor 7 through pharmacophore-based virtual screening and molecular docking approaches

Nasrin Saberi Harooni, Mohammad Reza Naimi-Jamal, Sajjad Gharaghani, Asal Katebi, Soheila Ajdary, Azar Tahghighi

published 29 Dec 2025

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Biocompatibility and antimicrobial efficacy of iodine-supported titania nanotubes on 3D-printed Ti-6Al-4V implants

Pariwat Taweekitikul, Abdul Azeez Abdu Aliyu, Nanthawan Jinakul, Amaraporn Wongrakpanich, Chedtha Puncreobutr, Jirapon Khamwannah, Boonrat Lohwongwatana, Saran Tantavisut

published 26 Dec 2025

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Functional beverage development from traditional Thai polyherbal tonic: Antioxidant-rich microcapsules and comprehensive sub-chronic toxicity assessment

Thammarat Kaewmanee, Acharaporn Issuriya, Piyapong Choochana, Pinanong Na-Phatthalung, Surasak Limsuwan, Sasitorn Chusri

published 23 Dec 2025

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Green synthesized silver nanoparticles from Moringa: Potential for preventative treatment of SARS-CoV-2 contaminated water

Omorilewa B. Ebunoluwa, Adebayo J. Bello, Rukayat O. Ayorinde, Nneka Onyejepu, Joseph O. Shaibu, Adeniyi R. Adewole, Abeebat O. Adewole, Olusegun A. Adedeji, Ololade O. Akinnusi, Olajumoke B. Oladapo, Temitope S. Popoola, Oluwamodupe M. Arotiba, Joseph B. Minari, Luqman A. Adams, Joy Okpuzor, Mujeeb O. Shittu

published 22 Dec 2025

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Evaluating the efficacy of intragastric botulinum toxin a injections with two different quantities and sites for obesity

Tien-Yow Chuang, Cheng-Hung Chiu, I-Wen Penn, Cheng-Di Chiu

published 19 Dec 2025

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Study on the release pattern of Zn in soil of ionic rare earth mining areas under different leaching conditions

Zhongqun Guo, Qiangqiang Liu, Feiyue Luo, Shaojun Xie, Tianhua Zhou

published 15 Dec 2025

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Preclinical safety and burn wound healing activity of “Novostron”, a novel topical iodine-based therapeutic

Nailya Ibragimova, Arailym Aitynova, Seitzhan Turganbay, Marina Lyu, Alexandr Ilin, Tamari Gapurkhaeva, Galina Ponomareva, Karina Vassilyeva, Diana Issayeva, Amirkan Azembayev, Serzhan Mombekov, Aralbek Rsaliyev, Nurgul Sikhayeva, Yergali Abduraimov, Saki Raheem

published 12 Dec 2025

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Machine learning-guided identification and simulation-based validation of potent JAK3 inhibitors for cancer therapy

Hailang Wei, Qingyun Wang

published 12 Dec 2025

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Impacts of polymorphisms in drug-metabolizing enzyme and transporter genes on irinotecan toxicity and efficacy in Thai colorectal cancer patients

Natthakul Akarapredee, Chalirmporn Atasilp, Chonlaphat Sukasem, Pimonpan Jinda, Rattanaporn Sukprasong, Jiraporn Jensuriyarkun, Soravit Wongjitjanyong, Patompong Satapornpong, Natchaya Vanwong

published 12 Dec 2025

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Caste- and age-specific venom composition of biogenic amines and the influence of diet in honey bees

Motoharu Hamano, Kazuya Niki, Keiki Imamura, Ken Sasaki

published 10 Dec 2025

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