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Cytotoxicity assay

Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay

Maelle Fontaine, Eline Bartolami, [ ... ], Marie Carriere

Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development

Wayne Yu, Mysore P. Ramprasad, [ ... ], Ying Buechler

The ribosome-inactivating proteins MAP30 and Momordin inhibit SARS-CoV-2

Norman R. Watts, Elif Eren, [ ... ], Paul T. Wingfield

Oxalic acid blocked the binding of spike protein from SARS-CoV-2 Delta (B.1.617.2) and Omicron (B.1.1.529) variants to human angiotensin-converting enzymes 2

Meng Wang, Huimin Yan, [ ... ], Lin Miao

Pneumolysin as a target for new therapies against pneumococcal infections: A systematic review

María Dolores Cima Cabal, Felipe Molina, [ ... ], María del Mar García-Suárez

Elucidating the effect of mechanical stretch stress on the mechanism of ligamentum flavum hypertrophy: Development of a novel in vitro multi-torsional stretch loading device

Woo-Keun Kwon, Chang Hwa Ham, [ ... ], Joo Han Kim

Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerases (PARPs), blocks in vitro replication of SARS-CoV-2 variants

Katherine E. Zarn, Sierra A. Jaramillo, [ ... ], Christopher T. French

Solubility affects IL-1β-producing activity of the synthetic candidalysin peptide

Taiki Mori, Hideo Kataoka, Gen Tanabe, Takeshi Into

Discovery of a novel natural product inhibitor of Clostridioides difficile with potent activity in vitro and in vivo

Rusha Pal, Mohamed N. Seleem

Absence of toxin gene transfer from Clostridioides difficile strain 630Δerm to nontoxigenic C. difficile strain NTCD-M3r in filter mating experiments

Susan P. Sambol, Stuart Johnson, Adam Cheknis, Dale N. Gerding

Aurintricarboxylic acid is a canonical disruptor of the TAZ-TEAD transcriptional complex

Kepeng Che, Ajaybabu V. Pobbati, [ ... ], Brian P. Rubin

Study from microcosms and mesocosms reveals Escherichia coli removal in high rate algae ponds during domestic wastewater treatment is primarily caused by dark decay

Paul Chambonniere, John E. Bronlund, Benoit Guieysse

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model

Dorjbal Dorjsuren, Richard T. Eastman, [ ... ], Anton Simeonov

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