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Thymocytes

RORγt inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apoptosis

Mia Collins, Rikard Pehrson, Hanna Grindebacke, Agnes Leffler, Marie Ramnegård, Helena Rannikmäe, Nina Krutrök, Linda Yrlid, Charlotte Pollard, Ian Dainty, Frank Narjes, Stefan von Berg, Antonio Llinas, Anna Malmberg, Jane McPheat, Eva Hansson, Elisabeth Bäck, Jenny Bernström, Thomas G. Hansson, David Keeling, Johan Jirholt

published 16 Jan 2025

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ATM-deficient murine thymic T-cell lymphoblastic lymphomas are PTEN-deficient and require AKT signaling for survival

Joseph B. An, Karen S. Hathcock, Seth M. Steinberg, Hyoyoung M. Choo-Wosoba, Richard J. Hodes

published 05 Dec 2024

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P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss

Heather E. Stefanski, Yan Xing, Jemma Nicholls, Leslie Jonart, Emily Goren, Patricia A. Taylor, Alea A. Mills, Megan Riddle, John McGrath, Jakub Tolar, Georg A. Hollander, Bruce R. Blazar

published 25 Jan 2022

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Brain-derived neurotrophic factor promotes immune reconstitution following radiation injury via activation of bone marrow mesenchymal stem cells

Guru Prasad Sharma, Anne C. Frei, Jayashree Narayanan, Tracy Gasperetti, Dana Veley, Asma Amjad, Katherine Albano, Brian L. Fish, Heather A. Himburg

published 25 Oct 2021

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A humanized CD3ε-knock-in mouse model for pre-clinical testing of anti-human CD3 therapy

Joel Crespo, Yi Ting Koh, Ningjie Hu, Paul A. Moore, Ezio Bonvini, Andrew L. Glasebrook, Andrea P. Martin, Robert J. Benschop

published 17 Feb 2021

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Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene

Jaafar Alomairi, Anne M. Molitor, Nori Sadouni, Saadat Hussain, Magali Torres, Wiam Saadi, Lan T. M. Dao, Guillaume Charbonnier, David Santiago-Algarra, Jean Christophe Andrau, Denis Puthier, Tom Sexton, Salvatore Spicuglia

published 26 May 2020

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Age-related transcriptional modules and TF-miRNA-mRNA interactions in neonatal and infant human thymus

Fernanda Bernardi Bertonha, Silvia Yumi Bando, Leandro Rodrigues Ferreira, Paulo Chaccur, Christiana Vinhas, Maria Claudia Nogueira Zerbini, Magda Maria Carneiro-Sampaio, Carlos Alberto Moreira-Filho

published 15 Apr 2020

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Histopathologic assessment of cultured human thymus

Laura P. Hale, Jadee Neff, Lynn Cheatham, Diana Cardona, M. Louise Markert, Joanne Kurtzberg

published 24 Mar 2020

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Developmental conservation of microRNA gene localization at the nuclear periphery

Eralda Salataj, Chrysoula Stathopoulou, Róbert A. Hafþórsson, Christoforos Nikolaou, Charalampos G. Spilianakis

published 04 Nov 2019

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γδ T cells shape memory-phenotype αβ T cell populations in non-immunized mice

Swati Popat Phalke, Yafei Huang, Kira Rubtsova, Andrew Getahun, Deming Sun, Richard L. Reinhardt, Rebecca L. O’Brien, Willi K. Born

published 25 Jun 2019

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The Notch signaling pathway controls CD8⁺ T cell differentiation independently of the classical effector HES1

Dave Maurice De Sousa, Frédéric Duval, Jean-François Daudelin, Salix Boulet, Nathalie Labrecque

published 05 Apr 2019

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The matricellular protein CCN5 inhibits fibrotic deformation of retinal pigment epithelium

Aeri Yoon, Sora Im, Juyeon Lee, Daeho Park, Dong Hyun Jo, Jin Hyoung Kim, Jeong Hun Kim, Woo Jin Park

published 20 Dec 2018

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Strain differences in thymic atrophy in rats immunized for EAE correlate with the clinical outcome of immunization

Mirjana Nacka-Aleksić, Marija Stojanović, Ivan Pilipović, Zorica Stojić-Vukanić, Duško Kosec, Gordana Leposavić

published 07 Aug 2018

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