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Tachyzoites

Early upregulation of immune suppressors dominates the macrophage response to Toxoplasma gondii

Dominykas Murza, Filip Lastovka, George Wood, Matthew P. Brember, Oliver Chan, James W. Ajioka, Betty Y. W. Chung

published 24 Nov 2025

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Repurposing the Medicines for Malaria Venture’s COVID Box to discover potent inhibitors of Toxoplasma gondii, and in vivo efficacy evaluation of almitrine bismesylate (MMV1804175) in chronically infected mice

Bruna Ramos dos Santos, Amanda Bruno da Silva Bellini Ramos, Renata Priscila Barros de Menezes, Marcus Tullius Scotti, Fábio Antônio Colombo, Marcos José Marques, Juliana Quero Reimão

published 07 Jul 2023

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Single- and duplex TaqMan-quantitative PCR for determining the copy numbers of integrated selection markers during site-specific mutagenesis in Toxoplasma gondii by CRISPR-Cas9

Kai Pascal Alexander Hänggeli, Andrew Hemphill, Norbert Müller, Bernd Schimanski, Philipp Olias, Joachim Müller, Ghalia Boubaker

published 16 Sep 2022

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Transcriptional signatures of clonally derived Toxoplasma tachyzoites reveal novel insights into the expression of a family of surface proteins

Terence C. Theisen, John C. Boothroyd

published 25 Feb 2022

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Computational image analysis reveals the structural complexity of Toxoplasma gondii tissue cysts

Neda Bauman, Andjelija Ilić, Olivera Lijeskić, Aleksandra Uzelac, Ivana Klun, Jelena Srbljanović, Vladimir Ćirković, Branko Bobić, Tijana Štajner, Olgica Djurković-Djaković

published 18 Aug 2020

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Proximity biotinylation reveals novel secreted dense granule proteins of Toxoplasma gondii bradyzoites

Santhosh Mukund Nadipuram, Amara Cervantes Thind, Shima Rayatpisheh, James Akira Wohlschlegel, Peter John Bradley

published 06 May 2020

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Characterisation of two Toxoplasma PROPPINs homologous to Atg18/WIPI suggests they have evolved distinct specialised functions

Hoa Mai Nguyen, Shuxian Liu, Wassim Daher, Feng Tan, Sébastien Besteiro

published 16 Apr 2018

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Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis

Juan D. Chaparro, Timmy Cheng, Uyen Phuong Tran, Rosa M. Andrade, Sara B. T. Brenner, Grace Hwang, Shara Cohn, Ken Hirata, James H. McKerrow, Sharon L. Reed

published 22 Mar 2018

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Development of an activity-based probe for acyl-protein thioesterases

Megan Garland, Christopher J. Schulze, Ian T. Foe, Wouter A. van der Linden, Matthew A. Child, Matthew Bogyo

published 24 Jan 2018

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Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites

Yuho Murata, Tatsuki Sugi, Louis M. Weiss, Kentaro Kato

published 13 Jun 2017

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Protection induced by virus-like particles containing Toxoplasma gondii microneme protein 8 against highly virulent RH strain of Toxoplasma gondii infection

Su-Hwa Lee, Ah-Ra Kim, Dong-Hun Lee, Ilaria Rubino, Hyo-Jick Choi, Fu-Shi Quan

published 13 Apr 2017

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Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling

Hyun Beom Song, Hyoung-Oh Jun, Jin Hyoung Kim, Young-Ha Lee, Min-Ho Choi, Jeong Hun Kim

published 13 Apr 2017

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An in vitro model of intestinal infection reveals a developmentally regulated transcriptome of Toxoplasma sporozoites and a NF-κB-like signature in infected host cells

Pascale S. Guiton, Janelle M. Sagawa, Heather M. Fritz, John C. Boothroyd

published 31 Mar 2017

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