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T helper cells

Limited efficacy of a therapeutic anti-CD40 monoclonal antibody to inhibit activated CD4 T cell autoimmunity in vitro

Chelsea Gootjes, Jaap Jan Zwaginga, Tatjana Nikolic, Bart O. Roep

published 12 Jun 2026

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Hypergammaglobulinemia in treated and untreated people with HIV

Isabel Vigmo, Staffan Nilsson, Aylin Yilmaz, Magnus Gisslén, Josefina Robertson, Johanna Karlsson

published 21 May 2026

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Characterizing the myeloid and lymphoid immune response in a porcine model of pulmonary ischemia-reperfusion injury through flow cytometry

Allen Duong, Andrea Mariscal, Lindsay Caldarone, Chun Xu, Lei Huang, Rayoun Ramendra, Shaf Keshavjee, Mingyao Liu, Stephen Juvet, Tereza Martinu

published 21 May 2026

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Identification and clinical implications of immune-related hub genes in psoriasis

Yuzhen Sun, Ziguang Zhou, Yu Mao, Niu Liu, Yanfeng Li, Weiyuan Fang

published 20 Apr 2026

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Genetic ablation of interleukin-17A augments fibrosis in a mouse model of cholestatic liver injury

Takashi Kitagataya, Anuradha Krishnan, Kirsta E. Olson, Florencia Gutierrez, Michelle Baez-Faria, Maria Eugenia Guicciardi, Kevin D. Pavelko, Adiba I. Azad, Gregory J. Gores

published 06 Feb 2026

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Association of tissue lymphocyte immunophenotype and clinical outcomes: A prospective study in patients with ulcerative colitis treated with vedolizumab

Katsuyoshi Ando, Shin Kashima, Aki Sakatani, Hiroaki Konishi, Atsuo Maemoto, Takahiro Ito, Masaki Taruishi, Kenichi Hamagami, Kaori Ishiguro, Mikihiro Fujiya

published 03 Feb 2026

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Prediction of immunogenicity of Rh antigens using in silico analysis of binding to human leukocyte antigen peptide, Basic/Translational Research

Hee-Jeong Youk, Yong-Joon Cho, Yong-Hyun Han, Seong Who Kim, Dae-Hyun Ko

published 27 Oct 2025

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Study on the effect of modified Liu-an decoction on Th1/Th2 function in Guinea pigs with cough variant asthma through the Notch signal pathway

Fangwei Xu, Jian Deng, Ningning Zhang, Kimberly XinTing Leow, Panpan Li, Chen Lu, Yuhang Chen, Ye Zhang, Liqun Wu

published 15 Sep 2025

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Low Th2 and high PD1⁺ TFh cells in blood predict remission after CTLA-4Ig treatment for 48 weeks in early rheumatoid arthritis

Tilia Selldén, Kerstin Andersson, Inger Gjertsson, Anna-Karin Hultgård Ekwall, Kristina Lend, Merete Lund Hetland, Mikkel Østergaard, Tillmann Uhlig, Marte Schrumpf Heiberg, Michael T. Nurmohamed, Jon Lampa, Tuulikki Sokka Isler, Dan Nordström, Kim Hørslev-Petersen, Bjorn Gudbjornsson, Gerdur Gröndal, Ronald van Vollenhoven, Cristina Maglio, Anna-Carin Lundell, Anna Rudin

published 28 Aug 2025

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HIV-1 controllers possess a unique CD8⁺ T cell activation phenotype and loss of control is associated with increased expression of exhaustion markers

Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase

published 28 Aug 2025

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Clinical manifestations and immune correlations in anti-centromere antibody-positive and anti-SSA/Ro antibody-positive primary Sjögren’s syndrome: A retrospective analysis

Songyan Zou, Riyi Zhang, Dongdong Yang, Xiaodong Li, Naixiang Huang, Fuyi Xie, Yinyu Mu

published 15 Aug 2025

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Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps

Ying Jin, Yuanshan Liang, Zhijun Wang, Yiting Jiang, Fayang Yuan, Tian Zhang

published 28 Jul 2025

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Ovalbumin-specific regulatory T cells differentiated from the naïve phenotype (CD44^loCD62L^hi) in mesenteric lymph nodes stably suppress enteropathy even in severe food-allergic mice

Kyoko Shibahara, Tomohiro Hoshino, Haruka Nakanishi, Kosuke Nishitsuji, Kohei Soga, Yoshiyo Bamba, Satoshi Hachimura, Haruyo Nakajima-Adachi

published 30 May 2025

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