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T helper cells

Genetic ablation of interleukin-17A augments fibrosis in a mouse model of cholestatic liver injury

Takashi Kitagataya, Anuradha Krishnan, Kirsta E. Olson, Florencia Gutierrez, Michelle Baez-Faria, Maria Eugenia Guicciardi, Kevin D. Pavelko, Adiba I. Azad, Gregory J. Gores

published 06 Feb 2026

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Association of tissue lymphocyte immunophenotype and clinical outcomes: A prospective study in patients with ulcerative colitis treated with vedolizumab

Katsuyoshi Ando, Shin Kashima, Aki Sakatani, Hiroaki Konishi, Atsuo Maemoto, Takahiro Ito, Masaki Taruishi, Kenichi Hamagami, Kaori Ishiguro, Mikihiro Fujiya

published 03 Feb 2026

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Prediction of immunogenicity of Rh antigens using in silico analysis of binding to human leukocyte antigen peptide, Basic/Translational Research

Hee-Jeong Youk, Yong-Joon Cho, Yong-Hyun Han, Seong Who Kim, Dae-Hyun Ko

published 27 Oct 2025

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Study on the effect of modified Liu-an decoction on Th1/Th2 function in Guinea pigs with cough variant asthma through the Notch signal pathway

Fangwei Xu, Jian Deng, Ningning Zhang, Kimberly XinTing Leow, Panpan Li, Chen Lu, Yuhang Chen, Ye Zhang, Liqun Wu

published 15 Sep 2025

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Low Th2 and high PD1⁺ TFh cells in blood predict remission after CTLA-4Ig treatment for 48 weeks in early rheumatoid arthritis

Tilia Selldén, Kerstin Andersson, Inger Gjertsson, Anna-Karin Hultgård Ekwall, Kristina Lend, Merete Lund Hetland, Mikkel Østergaard, Tillmann Uhlig, Marte Schrumpf Heiberg, Michael T. Nurmohamed, Jon Lampa, Tuulikki Sokka Isler, Dan Nordström, Kim Hørslev-Petersen, Bjorn Gudbjornsson, Gerdur Gröndal, Ronald van Vollenhoven, Cristina Maglio, Anna-Carin Lundell, Anna Rudin

published 28 Aug 2025

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HIV-1 controllers possess a unique CD8⁺ T cell activation phenotype and loss of control is associated with increased expression of exhaustion markers

Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase

published 28 Aug 2025

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Clinical manifestations and immune correlations in anti-centromere antibody-positive and anti-SSA/Ro antibody-positive primary Sjögren’s syndrome: A retrospective analysis

Songyan Zou, Riyi Zhang, Dongdong Yang, Xiaodong Li, Naixiang Huang, Fuyi Xie, Yinyu Mu

published 15 Aug 2025

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Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps

Ying Jin, Yuanshan Liang, Zhijun Wang, Yiting Jiang, Fayang Yuan, Tian Zhang

published 28 Jul 2025

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Ovalbumin-specific regulatory T cells differentiated from the naïve phenotype (CD44^loCD62L^hi) in mesenteric lymph nodes stably suppress enteropathy even in severe food-allergic mice

Kyoko Shibahara, Tomohiro Hoshino, Haruka Nakanishi, Kosuke Nishitsuji, Kohei Soga, Yoshiyo Bamba, Satoshi Hachimura, Haruyo Nakajima-Adachi

published 30 May 2025

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ABT-263, a BCL-2 inhibitor, selectively eliminates latently HIV-1-infected cells without viral reactivation

Jeong Eun Kang, Hyun Wook Seo, Dong-Eun Kim, Young Hyun Shin, Songmee Bae, Cheol-Hee Yoon

published 20 May 2025

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Rabies vaccination induces a CD4⁺ T_EM and CD4⁺CD8⁺ T_EMRA T_H1 phenotype in dogs

Haeree P. Lang, Farah F. Almeer, Marc K. Jenkins, Steven G. Friedenberg

published 12 May 2025

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The ubiquitin-like modifier FAT10 does not affect IL-12 expression and signaling

Jinjing Cao, Gerardo Omar Alvarez Salinas, Gunter Schmidtke, Michael Basler

published 06 May 2025

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Puriton attenuates the asthma severity in ovalbumin-induced murine model via balancing Th1/Th2 and inhibiting inflammation

So-Hyeon Bok, Hae Eun Jang, Kwang-Ho Kim, Dae-Hun Park

published 05 May 2025

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