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Synthetic genomics

A VPS33B CRISPR knockout study: In vitro evidence of an adhesion defect

Maria Caluianu, Kimberley A. Owen

published 13 Feb 2026

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Omics-aided design genome editing strategy for challenging human immortalized cell models

Patricia Mendoza-Garcia, Benjamin Keith, Markus Nordberg, Ella Quist, Cristina Ferrás, Ghaith M. Hamza, Ramy Elgendy, Stephanie Kay Ashenden, Jordi Chi, Natalie R. van Zuydam, Neil Hattersley, Xiang Zhang

published 12 Feb 2026

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Carbon nanotube and carbon dot mediated plasmid DNA delivery in cowpea leaves

Merve Saglam, Nikolaos Tsakirpaloglou, Aya Bridgeland, Robert Miller, Michael J. Thomson, Endang M. Septiningsih

published 27 Jan 2026

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Evolution of talent policies in Guangdong-Hong Kong-Macao greater bay area: An LDA thematic model approach

Jinpeng Wen, Hongxing Han

published 01 Dec 2025

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Investigating the impact of type I-E CRISPR-Cas systems and acrEI10 on multidrug-resistance in clinical isolates of Klebsiella pneumoniae

Maryam Siroosi, Fatemeh Ghasemi, Fereshteh Jabalameli, Mohammad Emaneini, Mohammadreza Salehi, Reza Beigverdi, Mohammad Ali Amoozegar

published 19 Nov 2025

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Improved CRISPR/Cas9 off-target prediction with DNABERT and epigenetic features

Kai Kimata, Kenji Satou

published 12 Nov 2025

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Genomic characteristics of Lacticaseibacillus rhamnosus strains isolated from blood

Piotr Jarocki, Jan Sadurski, Martyna Siuda, Mateusz Romanowicz, Jacek Panek, Magdalena Frąc, Adam Waśko

published 31 Oct 2025

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The genome of Gallaecimonas pentaromativorans strain 10A, isolated from a Pacific oyster, sheds light on an environmentally widespread genus with remarkable metabolic potential

Yasmine Gouin, Adam Wilcockson, Amy M. Chan, Curtis A. Suttle, Kevin Xu Zhong

published 21 Oct 2025

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Anti-cancer compound screening identifies Aurora Kinase A inhibition as a means to favor CRISPR/Cas9 gene correction over knock-out

Danny Wilbie, Selma Eising, Vicky Amo-Addae, Johanna Walther, Esmeralda Bosman, Zhiyong Lei, Olivier G de Jong, Jan J Molenaar, Enrico Mastrobattista

published 26 Sep 2025

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Off-target sequence variations driven by the intrinsic properties of the Cas–sgRNA–DNA complex in genome editing

Celine Kurniawan, Takeshi Itoh

published 18 Jul 2025

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pET28g: A Golden Gate-compatible pET vector for protein expression in Escherichia coli, validated by production of functional human ACE2

Inês M. Luís, Mariana Parada, João B. Vicente, Isabel A. Abreu

published 07 Jul 2025

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Comparative genomics of Lentilactobacillus buchneri reveals strain-level hyperdiversity and broad-spectrum CRISPR immunity against human and livestock gut phages

Ismail Gumustop, Ibrahim Genel, Ibrahim Cagri Kurt, Fatih Ortakci

published 10 Jun 2025

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Gene editing therapy as a therapeutic approach for cardiovascular diseases in animal models: A scoping review

Quan Duy Vo

published 04 Jun 2025

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