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Synthetic genome editing

Genetic regulatory axis between AGR2 and ESR1 promotes breast cancer progression

M. Aiman Mohtar, Delphine Fessart, Chia Yuh Cai, Syazalina Zahari, Saiful Effendi Syafruddin, Muhammad-Redha Abdullah-Zawawi, Valerie Le Morvan, Said Taouji, Ted Hupp

published 01 Jul 2026

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Non-viral in vivo electroporation-based chromosomal engineering and repair assessment in the murine uterine epithelium

Satoru Iwata, Yumi Miura, Takashi Iwamoto

published 11 May 2026

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Methylviologen resistance in loss-of-function mutants of the polyamine transporter gene OsLAT5

Kyrylo Schenstnyi, Zhengzhi Zhang, Bo Liu, Masayoshi Nakamura, Van Schepler-Luu, Eliza P. I. Loo, Bing Yang, Wolf B. Frommer

published 16 Apr 2026

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Single-tube two-step RPA-CRISPR/Cas12b platform for detection of Pseudomonas aeruginosa

Haotian Lin, Shichun Wang, Yuanhong Xie, Congyang Cheng, Junhua Jin, Xiaodong Song, Hongxing Zhang

published 18 Mar 2026

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A VPS33B CRISPR knockout study: In vitro evidence of an adhesion defect

Maria Caluianu, Kimberley A. Owen

published 13 Feb 2026

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Omics-aided design genome editing strategy for challenging human immortalized cell models

Patricia Mendoza-Garcia, Benjamin Keith, Markus Nordberg, Ella Quist, Cristina Ferrás, Ghaith M. Hamza, Ramy Elgendy, Stephanie Kay Ashenden, Jordi Chi, Natalie R. van Zuydam, Neil Hattersley, Xiang Zhang

published 12 Feb 2026

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Carbon nanotube and carbon dot mediated plasmid DNA delivery in cowpea leaves

Merve Saglam, Nikolaos Tsakirpaloglou, Aya Bridgeland, Robert Miller, Michael J. Thomson, Endang M. Septiningsih

published 27 Jan 2026

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Evolution of talent policies in Guangdong-Hong Kong-Macao greater bay area: An LDA thematic model approach

Jinpeng Wen, Hongxing Han

published 01 Dec 2025

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Investigating the impact of type I-E CRISPR-Cas systems and acrEI10 on multidrug-resistance in clinical isolates of Klebsiella pneumoniae

Maryam Siroosi, Fatemeh Ghasemi, Fereshteh Jabalameli, Mohammad Emaneini, Mohammadreza Salehi, Reza Beigverdi, Mohammad Ali Amoozegar

published 19 Nov 2025

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Improved CRISPR/Cas9 off-target prediction with DNABERT and epigenetic features

Kai Kimata, Kenji Satou

published 12 Nov 2025

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Genomic characteristics of Lacticaseibacillus rhamnosus strains isolated from blood

Piotr Jarocki, Jan Sadurski, Martyna Siuda, Mateusz Romanowicz, Jacek Panek, Magdalena Frąc, Adam Waśko

published 31 Oct 2025

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The genome of Gallaecimonas pentaromativorans strain 10A, isolated from a Pacific oyster, sheds light on an environmentally widespread genus with remarkable metabolic potential

Yasmine Gouin, Adam Wilcockson, Amy M. Chan, Curtis A. Suttle, Kevin Xu Zhong

published 21 Oct 2025

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Anti-cancer compound screening identifies Aurora Kinase A inhibition as a means to favor CRISPR/Cas9 gene correction over knock-out

Danny Wilbie, Selma Eising, Vicky Amo-Addae, Johanna Walther, Esmeralda Bosman, Zhiyong Lei, Olivier G de Jong, Jan J Molenaar, Enrico Mastrobattista

published 26 Sep 2025

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