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Substitution mutation

Analysis of the genotyping of circulating strains and characteristics of Glycoprotein E of Varicella-Zoster Virus in Shanxi Province, China

Hongye Liu, Peiyao Lv, Runmeng Ma, Shuping Guo, Ping Zhang, Jiane Guo, Ruihong Gao, Jitao Wang

published 03 Aug 2026

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Engineering of T7 DNA-dependent RNA polymerase with activity at elevated temperature

Svenja Hehn, Julia Gutbrod, Maxi Gutjahr, Andreas Marx

published 20 Jul 2026

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Design and in silico validation of donor DNA for RNA-guided recombinase-mediated knockout of mstnb gene in Labeo rohita

Lukram Sushil Singh, Porkodi Murugesan, Gowhar Iqbal, Nagavara C. Nidarshan, Harini Gunasekaran, Ad. Viralkumar, Kiran D. Rasal, Manoj P. Brahmane, Sunil K. Nayak, Arvind A. Sonwane, Mukunda Goswami

published 15 Jul 2026

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Genetic surveillance of first- and second-line drug-resistant isolates of Mycobacterium tuberculosis in Peru

David Santos-Lázaro, Aiko N. Vigo, Vidia V. Cotrina, Sandra Villar, Alexis Medina, Cynthia Julcapoma, Edson Pacheco, Miriam J. Alarcón, Zully M. Puyén

published 09 Jul 2026

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Featuring the application of biochemistry in dental practice through a self-directed assignment: A descriptive study

Nazlee Sharmin, Ava K. Chow

published 10 Apr 2026

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Genetic analysis of F1 cluster phages that infect Mycobacterium smegmatis identifies two distinct holin-like proteins that regulate the host lysis event

Richard S. Pollenz, Kira Ruiz-Houston, Wynter Dean, Loc Nguyen

published 07 Apr 2026

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Computational prediction of binding affinity and structural impact of three Pakistani SARS-CoV-2 spike RBD variants on human ACE2 interaction

Muhammad Usama, Muhammad Azeem, Ghulam Mustafa

published 01 Apr 2026

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Internal gene segments from a mouse-adapted influenza B virus confer increased pathogenicity to mice

Arne Matthys, Laura Amelinck, Anouk Smet, Tine Ysenbaert, Thorsten U. Vogel, Xavier Saelens, João Paulo Portela Catani

published 23 Mar 2026

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Near Neutral Selectionist Theories (NNST) for SARS-CoV-2 suggested by the substitution-mutation ratio (c/µ) analysis

Chun Wu, Nicholas J. Paradis

published 04 Mar 2026

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Potential phosphorylation of Liprin-α1 at threonine 701 regulates integrin-mediated cell motility

Martina Ramella, Daniele Brambilla, Sara Surini, Diletta Tonoli, Lucrezia Maria Ribolla, Ivan de Curtis

published 01 Dec 2025

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Integrating genomic epidemiology and deep mutational scanning data for prevalence forecasting of SARS-CoV-2 Omicron lineages

Zhong-yi Lei, Xiao-min Zhang, Jia-lu Han, Ji-guo Xue, Jia-yi Xu, Zi-lin Ren, Yi-gang Tong, Xiao-chen Bo, Ming Ni

published 03 Nov 2025

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Investigating the evolutionary dynamics and mutational pattern of SARS-CoV-2 spike gene on selected SARS-CoV-2 variants

Bachir Balech, Alessandra Lo Presti, Claudia Telegrafo, Lucia Maisto, Emanuela Giombini, Angela Di Martino, Luigina Ambrosio, Apollonia Tullo, Paola Stefanelli, on behalf of the Italian Genomic Laboratory Network

published 21 Oct 2025

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Spatiotemporal structure of SARS-CoV-2 mutational frequencies in wastewater samples from Ontario

Paula Magbor, William Z. Wang, Gopi Gugan, Abayomi S. Olabode, Devan G. Becker, Valeria R. Parreira, Opeyemi U. Lawal, Amber Fedynak, Linkang Zhang, Fozia Rizvi, Melinda Precious, Christopher T. DeGroot, Lawrence Goodridge, Art F. Y. Poon

published 16 Oct 2025

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