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Sphingolipids

Sphingolipid metabolism-related genes B4GALNT1 and CERS4 as prognostic biomarkers in lung adenocarcinoma

Jieun Jeon, Junho Kang, Jae-Hyung Park, Jae-Ho Lee, Dong Eun Kim, Woo-Jae Park, Shin Kim

published 10 Feb 2026

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Targeting ceramide metabolism to restore hypoxia-induced apoptosis in p53-deficient colon cancer cells

Karen Mechleb, Nancy Hourani, Maya Fakhry, Osama A. Alyamani, Rouba Hage-Sleiman, Hicham Younes, Antoine Abou Fayad, Nadia Soudani, Amer Sakr, Nadine Darwiche, Georges Nemer, Raya Saab, Marguerite Mrad, Ghassan Dbaibo

published 06 Jan 2026

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Evogliptin prevents ceramide-induced pyroptosis during calcification via modulation of NLRP3/GSDM-D mediated pathway in Vascular Smooth Muscle Cells

Razia Rashid Rahil, Salman Shamas, Nissar Ahmad Wani, Neha Nanda, Sheikh Fayaz Ahmad, Sabry Mohamed Attia, Abid Hamid, Mohammad Afzal Zargar, Owais Mohmad Bhat

published 03 Dec 2025

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Kummerowia striata extract protects paracetamol-induced liver injury by modulating the S1P/Nrf2/Keap1 pathway

Huanghui Qin, Runxiao Chen, Youlan Xie, Hang Liu, Yubo Xiao, Lanyu Li

published 14 Aug 2025

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Microsporidia infection alters C. elegans lipid levels

Hala Tamim El Jarkass, JiHae Jeon, Nicholas O. Burton, Aaron W. Reinke

published 01 Jul 2025

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Apolipoprotein and sphingolipid measurements: Can be used in the clinical practice of atrial fibrillation diagnosing and evaluating the cryoablation effectiveness?

Patrycja Bielawiec, Ewa Harasim-Symbor, Karolina Gołaszewska, Adrian Chabowski, Katarzyna Hodun, Klaudia Sztolsztener

published 04 Mar 2025

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Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model

Manuel E. Lopez, Daniel Wendt, Roger Lawrence, Kerui Gong, Hoonsan Ong, Bryan Yip, Joseph Chen, Linley Mangini, Britta Handyside, Alexander Giaramita, Aashish Lamichhane, Melanie Lo, Vishal Agrawal, Jeremy Van Vleet, Amanda Abolhesn, Jessica B. Felix, Isaac Villalpando, Vikas Bhat, Rolando De Angelis, Yuanbin Ru, Ayesha Khan, Sylvia Fong, Terri Christianson, Sherry Bullens, Brett E. Crawford, Stuart Bunting, Mika Aoyagi-Scharber

published 03 Jan 2025

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Lc—ms-based untargeted metabolomics reveals potential mechanisms of histologic chronic inflammation promoting prostate hyperplasia

Jiale Li, Beiwen Wu, Guorui Fan, Jie Huang, Zhiguo Li, Fenghong Cao

published 23 Dec 2024

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Synergistic effects of neuroprotective drugs with intravenous recombinant tissue plasminogen activator in acute ischemic stroke: A Bayesian network meta-analysis

Chun Dang, Qinxuan Wang, Yijia Zhuang, Qian Li, Yaoheng Lu, Ying Xiong, Li Feng

published 02 Dec 2024

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Pathway analysis of peripheral blood CD8+ T cell transcriptome shows differential regulation of sphingolipid signaling in multiple sclerosis and glioblastoma

Milan Stefanović, Ivan Jovanović, Maja Živković, Aleksandra Stanković

published 11 Jun 2024

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Effect of an eight-week high-intensity interval training programme on circulating sphingolipid levels in middle-aged adults at elevated cardiometabolic risk (SphingoFIT)—Protocol for a randomised controlled exercise trial

Justin Carrard, Manuel Hofer, Luisa Prechtl, Eva Fleischlin, Manuel Huber, Hector Gallart-Ayala, Tony Teav, Denis Infanger, Christoph Höchsmann, Karsten Koehler, Timo Hinrichs, Henner Hanssen, Julijana Ivanisevic, Arno Schmidt-Trucksäss

published 08 May 2024

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Comprehensive metabolomics of Philippine Stichopus cf. horrens reveals diverse classes of valuable small molecules for biomedical applications

Vicenzo Paolo M. Torreno, Ralph John Emerson J. Molino, Hiyas A. Junio, Eizadora T. Yu

published 06 Dec 2023

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Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors

Mikhail Rudinskiy, Maria Pons-Vizcarra, Tatiana Soldà, Ilaria Fregno, Timothy Jan Bergmann, Ana Ruano, Aida Delgado, Sara Morales, Xavier Barril, Manolo Bellotto, Elena Cubero, Ana María García-Collazo, Natalia Pérez-Carmona, Maurizio Molinari

published 29 Nov 2023

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