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Somatic mutation

Personalized genomic landscape of prostate cancer in African American men reveals novel drivers and therapeutic opportunities

Shanta Murthy, Katie Fago, James Knight, Keith Kowalczyk, Ryan Hankins, Gaurav Bandi, Anatoly Dritschilo, Mira Jung

published 14 Oct 2026

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Distinct NGS mutational landscape and prognostic implications in early-onset colorectal cancer: A dual-cohort analysis of TCGA PanCancer Atlas and MSK-IMPACT 50K

Elif Sertesen Çamöz, Osman Bilge Kaya, Hakan Erçelebi, Cengiz Karaçin, Yunus Kasım Terzi, Zerrin Yılmaz Çelik

published 01 Oct 2026

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Somatic mutation profiles in aged military nuclear test veterans: A comparative whole-genome sequence study

Justin Ofosu-Dankwa, Cristina Sisu, Rhona M. Anderson

published 30 Jun 2026

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SuperSelective PCR primers for determining cis/trans configurations of mutations within the same gene

Diana Yaneth Vargas, Fred Russell Kramer

published 18 May 2026

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Influence of the tumor microenvironment on genetic mutations in thyroid carcinoma

Lingyan Zhou, Shujian Xu, Yuwen Song, Dongqing Jiang, Shihong Chen

published 12 Feb 2026

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Variant calling in genomics: A comparative performance analysis and decision guide

Vera Pinto, Lisete Sousa, Carina Silva

published 05 Feb 2026

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Immortalization and characterization of Schwann cell lines derived from NF1-associated cutaneous neurofibromas

Hua Li, Alexander Pemov, Robert Allaway, David F. Muir, Lung-Ji Chang, Jineta Banerjee, Alexandra J. Scott, Jaime M.W. Nagy, Jian Liu, Meritxell Carrió, Helena Mazuelas, Anthony Yachnis, Sang Y. Lee, Xiaochun Zhang, Yang Lyu, Douglas R. Stewart, Angela Hirbe, Jaishri O. Blakeley, Eduard Serra, Deeann Wallis, Margaret R. Wallace

published 21 Jan 2026

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Whole genome sequencing revealed esophageal squamous cell carcinoma related biomarkers

Mingjun Li, Lei Li, Xizi Wang, Yanwei Zhao, Peina Du, Wei Wang, Zhenxing Wang, Yadong Wang, Yanxing Sheng, Mingliang Gu, Xiaodong Jia

published 26 Jun 2025

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Characterization of the genomic landscape of canine oral osteosarcoma reveals similarities with appendicular osteosarcoma

Christopher Husted, Sarah Adrianowycz, Cornelia Peterson, Suzanne Bartholf DeWitt, Elinor K. Karlsson, William Eward, Jason A. Somarelli, Kate Megquier, Heather L. Gardner

published 10 Jun 2025

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MAGNET-seq: A tandem PCR and hybrid capture method for enhanced target enrichment

Dongin Lee, Taehoon Kim, Duhee Bang

published 04 Jun 2025

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Genetic subtyping by Whole Exome Sequencing across Diffuse Large B Cell Lymphoma and Plasmablastic Lymphoma

Aitana Avendaño Pomares, Laura Rodríguez Merino, Sonia González, Jordi Morata, Raúl Tonda, Patricia Arribas, José Revert, Estrella Carrillo, Carlos Grande, Josep Maria Roncero, Jaime Pérez de Oteyza, Concepción Nicolás, Norma Gutierrez, Pau Abrisqueta, Antonio Gutiérrez, Ángel Ramírez-Páyer, Alejandro Martin Garcia-Sancho, Eva González-Barca, Santiago Montes-Moreno, on behalf of GELTAMO group (Grupo Español de Linfomas y Trasplante Autólogo de Medula Osea), Spain

published 11 Mar 2025

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The endometrial cancer A230V-ALK5 (TGFBR1) mutant attenuates TGF-β signaling and exhibits reduced in vitro sensitivity to ALK5 inhibitors

Eun-Jeong Yu, Daphne W. Bell

published 22 Nov 2024

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Computational investigation of missense somatic mutations in cancer and potential links to pH-dependence and proteostasis

Shalaw Sallah, Jim Warwicker

published 19 Nov 2024

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