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Solubility

Docking, Synthesis and Antiproliferative Activity of N-Acylhydrazone Derivatives Designed as Combretastatin A4 Analogues

Daniel Nascimento do Amaral, Bruno C. Cavalcanti, Daniel P. Bezerra, Paulo Michel P. Ferreira, Rosane de Paula Castro, José Ricardo Sabino, Camila Maria Longo Machado, Roger Chammas, Claudia Pessoa, Carlos M. R. Sant'Anna, Eliezer J. Barreiro, Lídia Moreira Lima

published 10 Mar 2014

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Soluble Prokaryotic Overexpression and Purification of Bioactive Human Granulocyte Colony-Stimulating Factor by Maltose Binding Protein and Protein Disulfide Isomerase

Bich Hang Do, Han-Bong Ryu, Phuong Hoang, Bon-Kyung Koo, Han Choe

published 03 Mar 2014

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Development of a Lozenge for Oral Transmucosal Delivery of Trans-Resveratrol in Humans: Proof of Concept

Otis L. Blanchard, Gregory Friesenhahn, Martin A. Javors, James M. Smoliga

published 26 Feb 2014

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Modified β-Cyclodextrin Inclusion Complex to Improve the Physicochemical Properties of Albendazole. Complete In Vitro Evaluation and Characterization

Agustina García, Darío Leonardi, Mario Oscar Salazar, María Celina Lamas

published 14 Feb 2014

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Automated NMR Fragment Based Screening Identified a Novel Interface Blocker to the LARG/RhoA Complex

Jia Gao, Rongsheng Ma, Wei Wang, Na Wang, Ryan Sasaki, David Snyderman, Jihui Wu, Ke Ruan

published 05 Feb 2014

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A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease

Daniel Todd, Ian Gowers, Simon J. Dowler, Michael D. Wall, George McAllister, David F. Fischer, Sipke Dijkstra, Silvina A. Fratantoni, Rhea van de Bospoort, Jessica Veenman-Koepke, Geraldine Flynn, Jamshid Arjomand, Celia Dominguez, Ignacio Munoz-Sanjuan, John Wityak, Jonathan A. Bard

published 04 Feb 2014

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Soluble Expression of Disulfide Bond Containing Proteins FGF15 and FGF19 in the Cytoplasm of Escherichia coli

Bo Kong, Grace L. Guo

published 20 Jan 2014

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A New Strategy for Enhancing the Oral Bioavailability of Drugs with Poor Water-Solubility and Low Liposolubility Based on Phospholipid Complex and Supersaturated SEDDS

Hui Zhou, Jiangling Wan, Lei Wu, Tao Yi, Wei Liu, Huibi Xu, Xiangliang Yang

published 31 Dec 2013

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In Vitro Determination of Drug Transfer from Drug-Coated Balloons

Anne Seidlitz, Nadine Kotzan, Stefan Nagel, Thomas Reske, Niels Grabow, Claus Harder, Svea Petersen, Katrin Sternberg, Werner Weitschies

published 31 Dec 2013

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Soluble Expression of Human Leukemia Inhibitory Factor with Protein Disulfide Isomerase in Escherichia coli and Its Simple Purification

A. Song Jung, Bon-Kyung Koo, Seon-Ha Chong, Kyunhoo Kim, Dong Kyu Choi, Thu Trang Thi Vu, Minh Tan Nguyen, Boram Jeong, Han-Bong Ryu, Injune Kim, Yeon Jin Jang, Robert Charles Robinson, Han Choe

published 16 Dec 2013

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Tat Peptide-Mediated Soluble Expression of the Membrane Protein LSECtin-CRD in Escherichia coli

Guofu Dong, Changzhen Wang, Yonghong Wu, Jianbo Cong, Li Cheng, Mingqun Wang, Pengkai Zhao, Li Tang, Chenggang Zhang, Ke Wu

published 16 Dec 2013

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Heterologous Expression of Mycobacterial Esx Complexes in Escherichia coli for Structural Studies Is Facilitated by the Use of Maltose Binding Protein Fusions

Mark A. Arbing, Sum Chan, Liam Harris, Emmeline Kuo, Tina T. Zhou, Christine J. Ahn, Lin Nguyen, Qixin He, Jamie Lu, Phuong T. Menchavez, Annie Shin, Thomas Holton, Michael R. Sawaya, Duilio Cascio, David Eisenberg

published 29 Nov 2013

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A Missense Mutation in CRYBB2 Leads to Progressive Congenital Membranous Cataract by Impacting the Solubility and Function of βB2-Crystallin

Weirong Chen, Xiaoyun Chen, Zhengmao Hu, Haotian Lin, Fengqi Zhou, Lixia Luo, Xinyu Zhang, Xiaojian Zhong, Ye Yang, Changrui Wu, Zhuoling Lin, Shaobi Ye, Yizhi Liu, for the study group of CCPMOH

published 28 Nov 2013

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