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Small molecules

The cellular uptake of angiogenin, an angiogenic and neurotrophic factor is through multiple pathways and largely dynamin independent

Ross Ferguson, Vasanta Subramanian

published 27 Feb 2018

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An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells

Katharina Schrade, Jessica Tröger, Adeeb Eldahshan, Kerstin Zühlke, Kamal R. Abdul Azeez, Jonathan M. Elkins, Martin Neuenschwander, Andreas Oder, Mohamed Elkewedi, Sarah Jaksch, Karsten Andrae, Jinliang Li, Joao Fernandes, Paul Markus Müller, Stephan Grunwald, Stephen F. Marino, Tanja Vukićević, Jenny Eichhorst, Burkhard Wiesner, Marcus Weber, Michael Kapiloff, Oliver Rocks, Oliver Daumke, Thomas Wieland, Stefan Knapp, Jens Peter von Kries, Enno Klussmann

published 26 Jan 2018

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Unraveling the novel effects of aroma from small molecules in preventing hen egg white lysozyme amyloid fibril formation

Zahra Seraj, Arefeh Seyedarabi, Ali Akbar Saboury, Mehran Habibi-Rezaei, Shahin Ahmadian, Atiyeh Ghasemi

published 22 Jan 2018

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Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery

Joey P. Ting, Frances Tung, Stephen Antonysamy, Stephen Wasserman, Spencer B. Jones, Feiyu F. Zhang, Alfonso Espada, Howard Broughton, Michael J. Chalmers, Michael E. Woodman, Holly A. Bina, Jeffrey A. Dodge, Jordi Benach, Aiping Zhang, Christopher Groshong, Danalyn Manglicmot, Marijane Russell, Sepideh Afshar

published 12 Jan 2018

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Biologicals and small molecules in psoriasis: A systematic review of economic evaluations

Christian Kromer, Daniel Celis, Diana Sonntag, Wiebke K. Peitsch

published 03 Jan 2018

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Small molecules targeting LapB protein prevent Listeria attachment to catfish muscle

Ali Akgul, Nawar Al-Janabi, Bhaskar Das, Mark Lawrence, Attila Karsi

published 18 Dec 2017

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Quantifying male and female pheromone-based mate choice in Caenorhabditis nematodes using a novel microfluidic technique

Flora Borne, Katja R. Kasimatis, Patrick C. Phillips

published 13 Dec 2017

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Structure-activity studies of Mdm2/Mdm4-binding stapled peptides comprising non-natural amino acids

Sharon Min Qi Chee, Jantana Wongsantichon, Jiawei Siau, Dawn Thean, Fernando Ferrer, Robert C. Robinson, David P. Lane, Christopher J. Brown, Farid J. Ghadessy

published 11 Dec 2017

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Conjugation of nitrated acetaminophen to Der p1 amplifies peripheral blood monocyte response to Der p1

Ryan G. Thomas, Brenda M. Rivera Reyes, Benjamin M. Gaston, Nelki B. Rivera Acosta, Ilya R. Bederman, Laura A. Smith, Morgan T. Sutton, Benlian Wang, John F. Hunt, Tracey L. Bonfield

published 11 Dec 2017

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Regulation of cAMP and GSK3 signaling pathways contributes to the neuronal conversion of glioma

Jinsoo Oh, Yongbo Kim, Lihua Che, Jeong Beom Kim, Gyeong Eon Chang, Eunji Cheong, Seok-Gu Kang, Yoon Ha

published 21 Nov 2017

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Identification of small molecules uncoupling the Notch::Jagged interaction through an integrated high-throughput screening

Natalia Platonova, Chiara Parravicini, Cristina Sensi, Alessandro Paoli, Michela Colombo, Antonino Neri, Ivano Eberini, Raffaella Chiaramonte

published 03 Nov 2017

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Levels of L-malate and other low molecular weight metabolites in spores of Bacillus species and Clostridium difficile

George Korza, Stephen Abini-Agbomson, Barbara Setlow, Aimee Shen, Peter Setlow

published 29 Aug 2017

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Novel application of the published kinase inhibitor set to identify therapeutic targets and pathways in triple negative breast cancer subtypes

Margarite D. Matossian, Steven Elliott, Van T. Hoang, Hope E. Burks, Theresa B. Phamduy, Douglas B. Chrisey, William J. Zuercher, David H. Drewry, Carrow Wells, Bridgette Collins-Burow, Matthew E. Burow

published 03 Aug 2017

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