Advertisement

Browse Subject Areas

?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

Small molecules

Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors

Thomas W. Miller, Joshua D. Amason, Elsa D. Garcin, Laurence Lamy, Patricia K. Dranchak, Ryan Macarthur, John Braisted, Jeffrey S. Rubin, Teresa L. Burgess, Catherine L. Farrell, David D. Roberts, James Inglese

published 05 Jul 2019

Loading metrics information...

Metrics unavailable. Please check back later.

Identifying small molecule probes of ENTPD5 through high throughput screening

Matthew A. Durst, Kiira Ratia, Arnon Lavie

published 26 Jun 2019

Loading metrics information...

Metrics unavailable. Please check back later.

Comparative biophysical characterization: A screening tool for acetylcholinesterase inhibitors

Devashree N. Patil, Sushama A. Patil, Srinivas Sistla, Jyoti P. Jadhav

published 31 May 2019

Loading metrics information...

Metrics unavailable. Please check back later.

Synthesis of hapten, generation of specific polyclonal antibody and development of ELISA with high sensitivity for therapeutic monitoring of crizotinib

Mona M. Al-Shehri, Adel S. El-Azab, Manal A. El-Gendy, Mohammed A. Hamidaddin, Ibrahim A. Darwish

published 11 Feb 2019

Loading metrics information...

Metrics unavailable. Please check back later.

A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN)

Joshua A. Sommers, Tomasz Kulikowicz, Deborah L. Croteau, Thomas Dexheimer, Dorjbal Dorjsuren, Ajit Jadhav, David J. Maloney, Anton Simeonov, Vilhelm A. Bohr, Robert M. Brosh Jr.

published 09 Jan 2019

Loading metrics information...

Metrics unavailable. Please check back later.

Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene

Sascha Stump, Tung-Chung Mou, Stephen R. Sprang, Nicholas R. Natale, Howard D. Beall

published 12 Oct 2018

Loading metrics information...

Metrics unavailable. Please check back later.

Simple changes of individual studies can improve the reproducibility of the biomedical scientific process as a whole

Matthias Steinfath, Silvia Vogl, Norman Violet, Franziska Schwarz, Hans Mielke, Thomas Selhorst, Matthias Greiner, Gilbert Schönfelder

published 12 Sep 2018

Loading metrics information...

Metrics unavailable. Please check back later.

Harnessing the biological complexity of Big Data from LINCS gene expression signatures

Aliyu Musa, Shailesh Tripathi, Meenakshisundaram Kandhavelu, Matthias Dehmer, Frank Emmert-Streib

published 29 Aug 2018

Loading metrics information...

Metrics unavailable. Please check back later.

Small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats

Vengadeshprabhu Karuppagounder, Anamika Bajpai, Shu Meng, Somasundaram Arumugam, Remya Sreedhar, Vijayasree V. Giridharan, Ashrith Guha, Arvind Bhimaraj, Keith A. Youker, Suresh S. Palaniyandi, Harry Karmouty-Quintana, Fadia Kamal, Kara L. Spiller, Kenichi Watanabe, Rajarajan A. Thandavarayan

published 19 Jul 2018

Loading metrics information...

Metrics unavailable. Please check back later.

Construction of an integrated database for hERG blocking small molecules

Tomohiro Sato, Hitomi Yuki, Keiji Ogura, Teruki Honma

published 06 Jul 2018

Loading metrics information...

Metrics unavailable. Please check back later.

High content, high-throughput screening for small molecule inducers of NF-κB translocation

Samuel Njikan, Alyssa J. Manning, Yulia Ovechkina, Divya Awasthi, Tanya Parish

published 28 Jun 2018

Loading metrics information...

Metrics unavailable. Please check back later.

Lack of acquired resistance in HER2-positive breast cancer cells after long-term HER2 siRNA nanoparticle treatment

Shenda Gu, Worapol Ngamcherdtrakul, Moataz Reda, Zhi Hu, Joe W. Gray, Wassana Yantasee

published 07 Jun 2018

Loading metrics information...

Metrics unavailable. Please check back later.

A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib

Amir Hossein Daneshmanesh, Mohammad Hojjat-Farsangi, Amineh Ghaderi, Ali Moshfegh, Lotta Hansson, Johan Schultz, Jan Vågberg, Styrbjörn Byström, Elisabeth Olsson, Thomas Olin, Anders Österborg, Håkan Mellstedt

published 01 Jun 2018

Loading metrics information...

Metrics unavailable. Please check back later.

Advertisement

Create a weekly email alert for: Small molecules

You can change these options by clicking profile then "Alerts and Notifications"