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Small molecules

In Vitro Assays Using Primary Embryonic Mouse Lymphatic Endothelial Cells Uncover Key Roles for FGFR1 Signalling in Lymphangiogenesis

Jan Kazenwadel, Genevieve A. Secker, Kelly L. Betterman, Natasha L. Harvey

Stability of Zinc Finger Nuclease Protein Is Enhanced by the Proteasome Inhibitor MG132

Suresh Ramakrishna, Young-Hoon Kim, Hyongbum Kim

A Cell-Based Small Molecule Screening Method for Identifying Inhibitors of Epithelial-Mesenchymal Transition in Carcinoma

Kian-Ngiap Chua, Wen-Jing Sim, [ ... ], Jean Paul Thiery

Interaction of 6 Mercaptopurine with Calf Thymus DNA – Deciphering the Binding Mode and Photoinduced DNA Damage

Sayeed Ur Rehman, Zahid Yaseen, [ ... ], Mohammad Tabish

Structure-based 3D-Pharmacophore modeling to discover novel interleukin 6 inhibitors: An in silico screening, molecular dynamics simulations and binding free energy calculations

Que-Huong Tran, Quoc-Thai Nguyen, [ ... ], Khac-Minh Thai

Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors

Thomas W. Miller, Joshua D. Amason, [ ... ], James Inglese

Binding-Site Assessment by Virtual Fragment Screening

Niu Huang, Matthew P. Jacobson

Label Free Fragment Screening Using Surface Plasmon Resonance as a Tool for Fragment Finding – Analyzing Parkin, a Difficult CNS Target

Karin Regnström, Jiangli Yan, [ ... ], Rick D. Artis

Addition of External Organic Carbon and Native Soil Organic Carbon Decomposition: A Meta-Analysis

Weidong Zhang, Xiaofeng Wang, Silong Wang

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell

Jude T. Deeney, Anna C. Belkina, [ ... ], Gerald V. Denis

Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II

Francesco Dituri, Antonio Mazzocca, [ ... ], Gianluigi Giannelli

Effective antibodies immobilization and functionalized nanoparticles in a quartz-crystal microbalance-based immunosensor for the detection of parathion

Bartolomeo Della Ventura, Marco Iannaccone, [ ... ], Raffaele Velotta

Fully Flexible Docking of Medium Sized Ligand Libraries with RosettaLigand

Samuel DeLuca, Karen Khar, Jens Meiler

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