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Small molecules

Peritoneal dialysis modality transition and impact on phosphate and potassium serum levels

Daniela Peruzzo, Murilo Guedes, [ ... ], on behalf of the BRAZPD Investigators

Dabrafenib, idelalisib and nintedanib act as significant allosteric modulator for dengue NS3 protease

R. V. Sriram Uday, Rajdip Misra, [ ... ], Nakul C. Maiti

Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells

Cameron Sadegh, Wataru Ebina, [ ... ], Jeffrey D. Macklis

A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin

Ruijie Zhang, Xiaozhi Yang, [ ... ], Jiayuh Lin

POT1 stability and binding measured by fluorescence thermal shift assays

Lynn W. DeLeeuw, Robert C. Monsen, [ ... ], Jonathan B. Chaires

Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics

Richard L. Cullum, Lauren M. Lucas, [ ... ], David J. Riese, II

The effects of selected biologics and a small molecule on Health-Related Quality of Life in adult plaque psoriasis patients: A systematic review and meta-analysis

Anna Karpińska-Mirecka, Joanna Bartosińska, Dorota Krasowska

How long do new medicines take to reach Canadian patients after companies file a submission: A cohort study

Joel Lexchin

Exposure to small molecule cocktails allows induction of neural crest lineage cells from human adipose-derived mesenchymal stem cells

Yuzo Takayama, Yuka Akagi, Yoichiro Shibuya, Yasuyuki S. Kida

Assessing multiple score functions in Rosetta for drug discovery

Shannon T. Smith, Jens Meiler

Pressure regulated basis for gene transcription by delta-cell micro-compliance modeled in silico: Biphenyl, bisphenol and small molecule ligand models of cell contraction-expansion

Hemant Sarin

A high-throughput screen identifies inhibitors of the interaction between the oncogenic transcription factor ERG and the cofactor EWS

Taylor R. Nicholas, Jingwei Meng, [ ... ], Peter C. Hollenhorst

G10 is a direct activator of human STING

Monali Banerjee, Sandip Middya, [ ... ], Arjun Surya

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