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Small molecules

Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

Anton Simeonov, Avanti Kulkarni, [ ... ], David M. Wilson III

Small Molecule, Non-Peptide p75^NTR Ligands Inhibit Aβ-Induced Neurodegeneration and Synaptic Impairment

Tao Yang, Juliet K. Knowles, [ ... ], Frank M. Longo

Small Molecule-Assisted, Line-Independent Maintenance of Human Pluripotent Stem Cells in Defined Conditions

Stefan Frank, Miao Zhang, Hans R. Schöler, Boris Greber

Plk1 Inhibition Causes Post-Mitotic DNA Damage and Senescence in a Range of Human Tumor Cell Lines

Denise L. Driscoll, Arijit Chakravarty, [ ... ], Marc L. Hyer

Crystal Structure of the FLT3 Kinase Domain Bound to the Inhibitor Quizartinib (AC220)

Julie A. Zorn, Qi Wang, [ ... ], John Kuriyan

Atomic Analysis of Protein-Protein Interfaces with Known Inhibitors: The 2P2I Database

Raphaël Bourgeas, Marie-Jeanne Basse, Xavier Morelli, Philippe Roche

WIKI4, a Novel Inhibitor of Tankyrase and Wnt/ß-Catenin Signaling

Richard G. James, Kathryn C. Davidson, [ ... ], Randall T. Moon

Discovery and Validation of a New Class of Small Molecule Toll-Like Receptor 4 (TLR4) Inhibitors

Matthew D. Neal, Hongpeng Jia, [ ... ], David J. Hackam

Why CCR2 and CCR5 Blockade Failed and Why CCR1 Blockade Might Still Be Effective in the Treatment of Rheumatoid Arthritis

Maria C. Lebre, Clarissa E. Vergunst, [ ... ], Paul P. Tak

Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors

Anneleen Van Hout, Thomas D’huys, [ ... ], Tom Van Loy

The Impact of Small Molecule Binding on the Energy Landscape of the Intrinsically Disordered Protein C-Myc

Julien Michel, Rémi Cuchillo

Identification and Characterization of Antifungal Compounds Using a Saccharomyces cerevisiae Reporter Bioassay

Brad Tebbets, Douglas Stewart, [ ... ], Bruce S. Klein

TAZ Expression as a Prognostic Indicator in Colorectal Cancer

Hiu-Fung Yuen, Cian M. McCrudden, [ ... ], WanJin Hong

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